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Epitope mapping of the protease resistant products of RT-QuIC does not allow the discrimination of sCJD subtypes

Sporadic Creutzfeldt-Jakob disease (sCJD) is a transmissible, rapidly progressive and fatal neurodegenerative disease. The transmissible agent linked to sCJD is composed of the misfolded form of the host-encoded prion protein. The combination of histopathological and biochemical analyses has allowed...

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Detalles Bibliográficos
Autores principales:	Piconi, Gabriele, Peden, Alexander H., Barria, Marcelo A., Green, Alison J. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576779/ https://www.ncbi.nlm.nih.gov/pubmed/31206560 http://dx.doi.org/10.1371/journal.pone.0218509

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