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Aggrecan is required for chondrocyte differentiation in ATDC5 chondroprogenitor cells
Aggrecan is an integral component of the extracellular matrix in cartilaginous tissues, including the growth plate. Heterozygous defects in the aggrecan gene have been identified as a cause of autosomal dominant short stature, bone age acceleration, and premature growth cessation. The mechanisms acc...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576788/ https://www.ncbi.nlm.nih.gov/pubmed/31206541 http://dx.doi.org/10.1371/journal.pone.0218399 |