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AMPK regulates germline stem cell quiescence and integrity through an endogenous small RNA pathway
During suboptimal growth conditions, Caenorhabditis elegans larvae undergo a global developmental arrest called “dauer.” During this stage, the germline stem cells (GSCs) become quiescent in an AMP-activated Protein Kinase (AMPK)-dependent manner, and in the absence of AMPK, the GSCs overproliferate...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576793/ https://www.ncbi.nlm.nih.gov/pubmed/31166944 http://dx.doi.org/10.1371/journal.pbio.3000309 |