Multidimensional analysis of Gammaherpesvirus RNA expression reveals unexpected heterogeneity of gene expression

Virus-host interactions are frequently studied in bulk cell populations, obscuring cell-to-cell variation. Here we investigate endogenous herpesvirus gene expression at the single-cell level, combining a sensitive and robust fluorescent in situ hybridization platform with multiparameter flow cytomet...

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Detalles Bibliográficos
Autores principales: Oko, Lauren M., Kimball, Abigail K., Kaspar, Rachael E., Knox, Ashley N., Coleman, Carrie B., Rochford, Rosemary, Chang, Tim, Alderete, Benjamin, van Dyk, Linda F., Clambey, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576797/
https://www.ncbi.nlm.nih.gov/pubmed/31166996
http://dx.doi.org/10.1371/journal.ppat.1007849

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