Early Initiation of Tocilizumab in Clinically Isolated Aortitis

Clinically isolated aortitis can arise from infectious or inflammatory etiologies. Glucocorticoids are the first-line therapy for inflammatory causes of aortitis such as large-vessel vasculitis. However, prolonged steroids use is associated with numerous side effects. We present a case of a 60-year-...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Irvin J, Pugh, Trevor, Liew, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579327/
https://www.ncbi.nlm.nih.gov/pubmed/31249756
http://dx.doi.org/10.7759/cureus.4479
_version_ 1783427860233453568
author Huang, Irvin J
Pugh, Trevor
Liew, Jean
author_facet Huang, Irvin J
Pugh, Trevor
Liew, Jean
author_sort Huang, Irvin J
collection PubMed
description Clinically isolated aortitis can arise from infectious or inflammatory etiologies. Glucocorticoids are the first-line therapy for inflammatory causes of aortitis such as large-vessel vasculitis. However, prolonged steroids use is associated with numerous side effects. We present a case of a 60-year-old woman with clinically isolated aortitis who received early treatment with tocilizumab to avoid prolonged steroid use.
format Online
Article
Text
id pubmed-6579327
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-65793272019-06-27 Early Initiation of Tocilizumab in Clinically Isolated Aortitis Huang, Irvin J Pugh, Trevor Liew, Jean Cureus Internal Medicine Clinically isolated aortitis can arise from infectious or inflammatory etiologies. Glucocorticoids are the first-line therapy for inflammatory causes of aortitis such as large-vessel vasculitis. However, prolonged steroids use is associated with numerous side effects. We present a case of a 60-year-old woman with clinically isolated aortitis who received early treatment with tocilizumab to avoid prolonged steroid use. Cureus 2019-04-16 /pmc/articles/PMC6579327/ /pubmed/31249756 http://dx.doi.org/10.7759/cureus.4479 Text en Copyright © 2019, Huang et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Huang, Irvin J
Pugh, Trevor
Liew, Jean
Early Initiation of Tocilizumab in Clinically Isolated Aortitis
title Early Initiation of Tocilizumab in Clinically Isolated Aortitis
title_full Early Initiation of Tocilizumab in Clinically Isolated Aortitis
title_fullStr Early Initiation of Tocilizumab in Clinically Isolated Aortitis
title_full_unstemmed Early Initiation of Tocilizumab in Clinically Isolated Aortitis
title_short Early Initiation of Tocilizumab in Clinically Isolated Aortitis
title_sort early initiation of tocilizumab in clinically isolated aortitis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579327/
https://www.ncbi.nlm.nih.gov/pubmed/31249756
http://dx.doi.org/10.7759/cureus.4479
work_keys_str_mv AT huangirvinj earlyinitiationoftocilizumabinclinicallyisolatedaortitis
AT pughtrevor earlyinitiationoftocilizumabinclinicallyisolatedaortitis
AT liewjean earlyinitiationoftocilizumabinclinicallyisolatedaortitis

Ejemplares similares