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FGF21 Signals Protein Status to the Brain and Adaptively Regulates Food Choice and Metabolism

Reduced dietary protein intake induces adaptive physiological changes in macronutrient preference, energy expenditure, growth, and glucose homeostasis. We demonstrate that deletion of the FGF21 co-receptor bKlotho (Klb) from the brain produces mice that are unable to mount a physiological response t...

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Detalles Bibliográficos
Autores principales:	Hill, Cristal M., Laeger, Thomas, Dehner, Madeleine, Albarado, Diana C., Clarke, Blaise, Wanders, Desiree, Burke, Susan J., Collier, J. Jason, Qualls-Creekmore, Emily, Solon-Biet, Samantha M., Simpson, Stephen J., Berthoud, Hans-Rudolf, Munzberg, Heike, Morrison, Christopher D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579533/ https://www.ncbi.nlm.nih.gov/pubmed/31167139 http://dx.doi.org/10.1016/j.celrep.2019.05.022

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