Sildenafil, a phosphodiesterase type 5 inhibitor, augments sphincter bursting and bladder afferent activity to enhance storage function and voiding efficiency in mice

OBJECTIVES: To investigate the influence of low‐dose sildenafil, a phosphodiesterase type 5 inhibitor (PDE5‐I), on the function of the mouse lower urinary tract (LUT). MATERIALS AND METHODS: Adult male mice were decerebrated and arterially perfused with a carbogenated Ringer's solution to estab...

Descripción completa

Detalles Bibliográficos
Autores principales: Ito, Hiroki, Chakrabarty, Basu, Drake, Marcus J., Fry, Christopher H., Kanai, Anthony J., Pickering, Anthony E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Translational Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579678/
https://www.ncbi.nlm.nih.gov/pubmed/30636087
http://dx.doi.org/10.1111/bju.14664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579678/
https://www.ncbi.nlm.nih.gov/pubmed/30636087
http://dx.doi.org/10.1111/bju.14664

Ejemplares similares