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Toward a Model for Activation of Orai Channel

Store-operated calcium release-activated calcium (CRAC) channels mediate a variety of cellular signaling functions. The CRAC channel pore-forming protein, Orai1, is a hexamer arranged with 3-fold symmetry. Despite its importance in moving Ca(2+) ions into cells, a detailed mechanistic understanding...

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Detalles Bibliográficos
Autores principales: Dong, Hao, Zhang, Yiming, Song, Ruiheng, Xu, Jingjie, Yuan, Yigao, Liu, Jindou, Li, Jia, Zheng, Sisi, Liu, Tiantian, Lu, Benzhuo, Wang, Youjun, Klein, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579751/
https://www.ncbi.nlm.nih.gov/pubmed/31207498
http://dx.doi.org/10.1016/j.isci.2019.05.041