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Role of T Cell-To-Dendritic Cell Chemoattraction in T Cell Priming Initiation in the Lymph Node: An Agent-Based Modeling Study
The adaptive immune response is initiated in lymph nodes by contact between antigen-bearing dendritic cells (DCs) and antigen-specific T cells. A selected number of naïve T cells that recognize a specific antigen may proliferate into expanded clones, differentiate, and acquire an effector phenotype....
Autores principales: | Azarov, Ivan, Peskov, Kirill, Helmlinger, Gabriel, Kosinsky, Yuri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579912/ https://www.ncbi.nlm.nih.gov/pubmed/31244840 http://dx.doi.org/10.3389/fimmu.2019.01289 |
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