Flagellin/NLRC4 Pathway Rescues NLRP3-Inflammasome Defect in Dendritic Cells From HIV-Infected Patients: Perspective for New Adjuvant in Immunocompromised Individuals

Introduction: NLRP3 inflammasome plays a key role in dendritic cells (DC) activation in response to vaccine adjuvants, however we previously showed that it is not properly activated in DC from HIV-infected patients (HIV-DC), explaining, at least in part, the poor response to immunization of these pa...

Descripción completa

Detalles Bibliográficos
Autores principales: dos Reis, Edione Cristina, Leal, Vinícius Nunes Cordeiro, Soares, Jaíne Lima da Silva, Fernandes, Fernanda Pereira, Souza de Lima, Dhêmerson, de Alencar, Bruna Cunha, Pontillo, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579915/
https://www.ncbi.nlm.nih.gov/pubmed/31244842
http://dx.doi.org/10.3389/fimmu.2019.01291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579915/
https://www.ncbi.nlm.nih.gov/pubmed/31244842
http://dx.doi.org/10.3389/fimmu.2019.01291

Ejemplares similares