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TFAP2E methylation promotes 5-fluorouracil resistance via exosomal miR-106a-5p and miR-421 in gastric cancer MGC-803 cells

Hypermethylation of transcription factor activating enhancer-binding protein 2e (TFAP2E) has been reported to be associated with chemoresistance to 5-fluorouracil (5-FU) in gastric cancer (GC). In the present study, the molecular mechanism governing this chemoresistance was investigated. Drug-resist...

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Detalles Bibliográficos
Autores principales:	Jingyue, Sun, Xiao, Wang, Juanmin, Zha, Wei, Li, Daoming, Li, Hong, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579997/ https://www.ncbi.nlm.nih.gov/pubmed/31115533 http://dx.doi.org/10.3892/mmr.2019.10237

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