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Crocin protects against dexamethasone-induced osteoblast apoptosis by inhibiting the ROS/Ca(2+)-mediated mitochondrial pathway
Osteoblast apoptosis has been identified as an important event in the development of glucocorticoid (GC)-induced osteoporosis and osteonecrosis of the femoral head. Crocin, a bioactive ingredient of saffron, has been demonstrated to induce antiapoptotic effects on numerous types of cell in vitro; ho...
Autores principales: | Nie, Zhigang, Deng, Shuang, Zhang, Lei, Chen, Sen, Lu, Qiang, Peng, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580004/ https://www.ncbi.nlm.nih.gov/pubmed/31115574 http://dx.doi.org/10.3892/mmr.2019.10267 |
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