Telomere Maintenance-Associated PML Is a Potential Specific Therapeutic Target of Human Colorectal Cancer

Telomere length maintenance is essential for cell proliferation, which is particularly prominent in cancer. We validate that the primary colorectal tumors exhibit heterogeneous telomere lengths but mostly (90%) short telomeres relative to normal tissues. Intriguingly, relatively short telomeres are...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Peng, Wang, Hua, Zhang, Jingsong, Fu, Yudong, Zhu, Zhengmao, Wang, Jinmiao, Yin, Yu, Wang, Haiying, Zhou, Zhongcheng, Yang, Jiao, Liu, Linlin, Gou, Mo, Zeng, Ming, Yuan, Jinghua, Wang, Feng, Pan, Xinghua, Xiang, Rong, Weissman, Sherman M., Qi, Feng, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580093/
https://www.ncbi.nlm.nih.gov/pubmed/31207547
http://dx.doi.org/10.1016/j.tranon.2019.05.010

Ejemplares similares

Ejemplares similares