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IGF1R facilitates epithelial-mesenchymal transition and cancer stem cell properties in neuroblastoma via the STAT3/AKT axis

BACKGROUND: Neuroblastoma (NB) displays the most heterogeneity in clinical manifestation. The insulin-like growth factor 1 receptor (IGF1R) has long been recognized for its role in tumourigenesis and growth. The IGF/IGF1R pathway is important in maintaining cell survival. It is reported that IGF1R p...

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Detalles Bibliográficos
Autores principales:	Wang, Xiao-Hui, Wu, Hai-Ying, Gao, Jian, Wang, Xu-Hui, Gao, Tian-Hui, Zhang, Shu-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580139/ https://www.ncbi.nlm.nih.gov/pubmed/31354352 http://dx.doi.org/10.2147/CMAR.S196862

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