Cargando…

Cerebral Dopamine Neurotrophic Factor Diffuses Around the Brainstem and Does Not Undergo Anterograde Transport After Injection to the Substantia Nigra

Cerebral dopamine neurotrophic factor (CDNF) has shown therapeutic potential in rodent and non-human primate models of Parkinson’s disease by protecting the dopamine neurons from degeneration and even restoring their phenotype and function. Previously, neurorestorative efficacy of CDNF in the 6-hydr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Albert, Katrina, Renko, Juho-Matti, Mätlik, Kert, Airavaara, Mikko, Voutilainen, Merja H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580362/ https://www.ncbi.nlm.nih.gov/pubmed/31244598 http://dx.doi.org/10.3389/fnins.2019.00590

Ejemplares similares

AAV Vector-Mediated Gene Delivery to Substantia Nigra Dopamine Neurons: Implications for Gene Therapy and Disease Models
por: Albert, Katrina, et al.
Publicado: (2017)

Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra
por: Mätlik, Kert, et al.
Publicado: (2017)

Implementation of deep neural networks to count dopamine neurons in substantia nigra
por: Penttinen, Anna‐Maija, et al.
Publicado: (2018)

Isolated substantia nigra involvement in brainstem demyelination
por: Mahale, Rohan R., et al.
Publicado: (2015)

Neuroprotective and reparative effects of endoplasmic reticulum luminal proteins – mesencephalic astrocyte-derived neurotrophic factor and cerebral dopamine neurotrophic factor
por: Albert, Katrina, et al.
Publicado: (2019)

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Elevates Stimulus-Evoked Release of Dopamine in Freely-Moving Rats
por: Renko, Juho-Matti, et al.
Publicado: (2018)

Operant Self-Stimulation of Dopamine Neurons in the Substantia Nigra
por: Rossi, Mark A., et al.
Publicado: (2013)

Soemmerring and the Substantia Nigra
por: Faull, R. L. M, et al.
Publicado: (1968)

Dopamine Pathology in Schizophrenia: Analysis of Total and Phosphorylated Tyrosine Hydroxylase in the Substantia Nigra
por: Perez-Costas, Emma, et al.
Publicado: (2012)

Environmental and behavioral modulation of the number of substantia nigra dopamine neurons in adult mice
por: Aumann, Tim D, et al.
Publicado: (2013)

Coexistence of glutamatergic spine synapses and shaft synapses in substantia nigra dopamine neurons
por: Jang, Miae, et al.
Publicado: (2015)

Dopamine neuronal protection in the mouse Substantia nigra by GHSR is independent of electric activity
por: Stutz, Bernardo, et al.
Publicado: (2019)

Stress Controllability Modulates Basal Activity of Dopamine Neurons in the Substantia Nigra Compacta
por: Yao, Li, et al.
Publicado: (2021)

Activity-dependent somatodendritic dopamine release in the substantia nigra autoinhibits the releasing neuron
por: Hikima, Takuya, et al.
Publicado: (2021)

Glial Cell Line–Derived Neurotrophic Factor Receptor Rearranged During Transfection Agonist Supports Dopamine Neurons In Vitro and Enhances Dopamine Release In Vivo
por: Mahato, Arun Kumar, et al.
Publicado: (2019)

Electroacupuncture-regulated neurotrophic factor mRNA expression in the substantia nigra of Parkinson's disease rats
por: Wang, Shuju, et al.
Publicado: (2013)

Interleukin-4 Contributes to Degeneration of Dopamine Neurons in the Lipopolysaccharide-treated Substantia Nigra in vivo
por: Bok, Eugene, et al.
Publicado: (2018)

Early Dysfunction of Substantia Nigra Dopamine Neurons in the ParkinQ311X Mouse
por: Regoni, Maria, et al.
Publicado: (2021)

Preservation of dendritic D2 receptor transmission in substantia nigra dopamine neurons with age
por: Troyano-Rodriguez, Eva, et al.
Publicado: (2023)

Substantia nigra dopaminergic neurons and striatal interneurons are engaged in three parallel but interdependent postnatal neurotrophic circuits
por: Ortega‐de San Luis, Clara, et al.
Publicado: (2018)

Functional Upregulation of Ca(2+) -Activated K(+) Channels in the Development of Substantia Nigra Dopamine Neurons
por: Ramírez-Latorre, José A.
Publicado: (2012)

T-type calcium channels trigger a hyperpolarization induced afterdepolarization in substantia nigra dopamine neurons
por: Evans, Rebekah C, et al.
Publicado: (2015)

Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo
por: Albert, Katrina, et al.
Publicado: (2021)

Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigra
por: Nadella, Rasajna, et al.
Publicado: (2014)

The history of the research of iron in parkinsonian substantia nigra
por: Friedman, Andrzej, et al.
Publicado: (2012)

Nicotine impact on rat substantia nigra compacta
por: Elgayar, Sanaa A M, et al.
Publicado: (2021)

Dopamine Reduction in the Substantia Nigra of Parkinson's Disease Patients Confirmed by In Vivo Magnetic Resonance Spectroscopic Imaging
por: Gröger, Adriane, et al.
Publicado: (2014)

Substantia nigra micro-haemorrhage causing ipsilateral unilateral Parkinsonism and abnormal dopamine transporter scan uptake
por: Ghoneim, Aliaa, et al.
Publicado: (2020)

Gut microbiota relieves inflammation in the substantia nigra of chronic Parkinson's disease by protecting the function of dopamine neurons
por: Zhang, Tian, et al.
Publicado: (2022)

Picornavirus May Be Linked to Parkinson’s Disease through Viral Antigen in Dopamine-Containing Neurons of Substantia Nigra
por: Niklasson, Bo, et al.
Publicado: (2022)

Enhanced training protects memory against amnesia produced by concurrent inactivation of amygdala and striatum, amygdala and substantia nigra, or striatum and substantia nigra
por: Salado-Castillo, Rigoberto, et al.
Publicado: (2011)

Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats
por: Renko, Juho-Matti, et al.
Publicado: (2021)

State transitions in the substantia nigra reticulata predict the onset of motor deficits in models of progressive dopamine depletion in mice
por: Willard, Amanda M, et al.
Publicado: (2019)

A dual role for α-synuclein in facilitation and depression of dopamine release from substantia nigra neurons in vivo
por: Somayaji, Mahalakshmi, et al.
Publicado: (2020)

Proteome analysis of human substantia nigra in Parkinson's disease
por: Werner, Cornelius J, et al.
Publicado: (2008)

Bidirectional Modulation of Substantia Nigra Activity by Motivational State
por: Rossi, Mark A., et al.
Publicado: (2013)

Epstein-Barr virus encephalitis with substantia nigra involvement
por: Çelik, Tamer, et al.
Publicado: (2015)

Mesencephalic origin of the rostral Substantia nigra pars reticulata
por: Madrigal, M. Pilar, et al.
Publicado: (2015)

Glucocerebrosidase Deficiency in Substantia Nigra of Parkinson Disease Brains
por: Gegg, Matthew E, et al.
Publicado: (2012)

Degeneration of the Substantia Nigra Following Ipsilateral Striatal Infarction
por: Ohtomo, Gaku, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_rrgguo0d909bma36m2fl7d18vd