Cargando…

A new mouse model to study the role of ectopic Nanos3 expression in cancer

BACKGROUND: NANOS3 is a gene conserved throughout evolution. Despite the quite low conservation of Nanos sequences between different organisms and even between Nanos paralogs, their role in germ cell development is remarkably universal. Human Nanos3 expression is normally restricted to the gonads an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Andries, Vanessa, De Keuckelaere, Evi, Staes, Katrien, Hochepied, Tino, Taminau, Joachim, Lemeire, Kelly, Birembaut, Philippe, Berx, Geert, van Roy, Frans
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580527/ https://www.ncbi.nlm.nih.gov/pubmed/31208373 http://dx.doi.org/10.1186/s12885-019-5807-x

Ejemplares similares

Innovative mouse models for the tumor suppressor activity of Protocadherin-10 isoforms
por: Kleinberger, Irene, et al.
Publicado: (2022)

p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification
por: Pieters, Tim, et al.
Publicado: (2016)

Myb drives B-cell neoplasms and myeloid malignancies in vivo
por: Pieters, Tim, et al.
Publicado: (2022)

A Constitutional Translocation t(1;17)(p36.2;q11.2) in a Neuroblastoma Patient Disrupts the Human NBPF1 and ACCN1 Genes
por: Vandepoele, Karl, et al.
Publicado: (2008)

NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest
por: Andries, Vanessa, et al.
Publicado: (2015)

Human decellularized dermal matrix seeded with adipose-derived stem cells enhances wound healing in a murine model: Experimental study
por: Doornaert, M., et al.
Publicado: (2019)

GC Content of Early Metazoan Genes and Its Impact on Gene Expression Levels in Mammalian Cell Lines
por: Gul, Ismail Sahin, et al.
Publicado: (2018)

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies
por: Pieters, Tim, et al.
Publicado: (2019)

The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression
por: Berx, Geert, et al.
Publicado: (2001)

Efficient and User-Friendly Pluripotin-based Derivation of Mouse Embryonic Stem Cells
por: Pieters, Tim, et al.
Publicado: (2011)

ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition
por: Skrypek, Nicolas, et al.
Publicado: (2018)

A New Transgenic Mouse Line for Imaging Mitochondrial Calcium Signals
por: Redolfi, Nelly, et al.
Publicado: (2021)

Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice
por: Pieters, Tim, et al.
Publicado: (2021)

Sterile triggers drive joint inflammation in TNF‐ and IL‐1β‐dependent mouse arthritis models
por: Thiran, Alexandra, et al.
Publicado: (2023)

Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma
por: De Thaye, Elien, et al.
Publicado: (2020)

The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2
por: Scott, Charlotte L., et al.
Publicado: (2016)

Ectopic chondrogenesis of nude mouse induced by nano gene delivery enhanced tissue engineering technology
por: Zhang, Guangcheng, et al.
Publicado: (2019)

The Role of Epithelial-to-Mesenchymal Plasticity in Ovarian Cancer Progression and Therapy Resistance
por: Loret, Nele, et al.
Publicado: (2019)

The Transcriptional Repressor Kaiso Localizes at the Mitotic Spindle and Is a Constituent of the Pericentriolar Material
por: Soubry, Adelheid, et al.
Publicado: (2010)

Melanoma Cells Revive an Embryonic Transcriptional Network to Dictate Phenotypic Heterogeneity
por: Vandamme, Niels, et al.
Publicado: (2014)

NLRP2 controls age-associated maternal fertility
por: Kuchmiy, Anna A., et al.
Publicado: (2016)

Snail in the frame of malignant tumor recurrence
por: De Craene, Bram, et al.
Publicado: (2006)

Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair
por: Marine, Jean-Christophe, et al.
Publicado: (2009)

Ectopic callose deposition into woody biomass modulates the nano-architecture of macrofibrils
por: Bourdon, Matthieu, et al.
Publicado: (2023)

SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell–cell junctions
por: Vandewalle, Cindy, et al.
Publicado: (2005)

Association of Cell Death Markers With Tumor Immune Cell Infiltrates After Chemo-Radiation in Cervical Cancer
por: Oltean, Teodora, et al.
Publicado: (2022)

Mouse Muscle As an Ectopic Permissive Site for Human Pancreatic Development
por: Capito, Carmen, et al.
Publicado: (2013)

Learning causal models of multivariate systems: and the value of IT for the performance modeling of computer programs
por: Lemeire, Jan
Publicado: (2007)

Combined subtractive cDNA cloning and array CGH: an efficient approach for identification of overexpressed genes in DNA amplicons
por: De Preter, Katleen, et al.
Publicado: (2004)

Ectopic Osteogenesis and Scaffold Biodegradation of Nano-Hydroxyapatite-Chitosan in a Rat Model
por: He, Yiqun, et al.
Publicado: (2015)

Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression
por: Foubert, Ellen, et al.
Publicado: (2010)

A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8
por: Bouhy, Delphine, et al.
Publicado: (2017)

OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection
por: Verboom, Lien, et al.
Publicado: (2023)

Intrinsic Balance between ZEB Family Members Is Important for Melanocyte Homeostasis and Melanoma Progression
por: Bruneel, Kenneth, et al.
Publicado: (2020)

Genetic mapping of species differences via in vitro crosses in mouse embryonic stem cells
por: Lazzarano, Stefano, et al.
Publicado: (2018)

Voluntary Resistance Running as a Model to Induce mTOR Activation in Mouse Skeletal Muscle
por: D’Hulst, Gommaar, et al.
Publicado: (2019)

Preclinical humanized mouse model with ectopic ovarian tissues
por: FU, SHILONG, et al.
Publicado: (2014)

Novel insights into mouse models of ectopic proplatelet release
por: Spindler, Markus, et al.
Publicado: (2022)

Ectopic pregnancy: when is expectant management safe?
por: Rodrigues, Sharon P., et al.
Publicado: (2012)

Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-β1
por: Carceller, Elena, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_d282mgu0j48f8444q809i4frnd