Nerve growth factor promotes the proliferation of Müller cells co-cultured with internal limiting membrane by regulating cell cycle via Trk-A/PI3K/Akt pathway

BACKGROUND: Nerve growth factor (NGF), produced by Müller cells, and internal limiting membrane (ILM) have fundamental roles in the development of full-thickness macular hole (FTMH). However, the potential crosstalk between NGF and ILM in FTMH is unclear. This study aimed to explore the mechanism an...

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Detalles Bibliográficos
Autores principales: Zhang, Luyi, Li, Xiaoxia, Lin, Xiaoqin, Wu, Miaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580575/
https://www.ncbi.nlm.nih.gov/pubmed/31208396
http://dx.doi.org/10.1186/s12886-019-1142-x

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