Cargando…
Tumor-targeted IL-12 combined with tumor resection yields a survival-favorable immune profile
BACKGROUND: Although accumulated evidence provides a strong scientific premise for using immune profiles to predict survival in patients with cancer, a universal immune profile across tumor types is still lacking, and how to achieve a survival-associated immune profile remains to be evaluated. METHO...
Autores principales: | Zhao, Qingnan, Hu, Jiemiao, Mitra, Abhisek, Cutrera, Jeffry, Zhang, Wendong, Zhang, Zhongting, Yan, Jun, Xia, Xueqing, Mahadeo, Kris Michael, Livingston, John Andrew, Gorlick, Richard, Li, Shulin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580640/ https://www.ncbi.nlm.nih.gov/pubmed/31208461 http://dx.doi.org/10.1186/s40425-019-0631-z |
Ejemplares similares
-
Cell membrane-anchored and tumor-targeted IL-12 (attIL12)-T cell therapy for eliminating large and heterogeneous solid tumors
por: Hu, Jiemiao, et al.
Publicado: (2022) -
Induction of NKG2D ligand expression on tumor cells by CD8(+) T cell engagement-mediated activation of nuclear factor-kappa B and p300/CBP-associated factor
por: Hu, Jiemiao, et al.
Publicado: (2019) -
WSX1 Expression in Tumors Induces Immune Tolerance via Suppression of Effector Immune Cells
por: Dibra, Denada, et al.
Publicado: (2011) -
IL27 controls skin tumorigenesis via accumulation of ETAR-positive CD11b cells in the pre-malignant skin
por: Dibra, Denada, et al.
Publicado: (2016) -
IL12 immune therapy clinical trial review: Novel strategies for avoiding CRS-associated cytokines
por: Jia, Zhiliang, et al.
Publicado: (2022)