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Periodicity and dosage optimization of an RNAi model in eukaryotes cells
BACKGROUND: As a highly efficient and specific gene regulation technology, RNAi has broad application fields and good prospects. The effect of RNAi enhances as the dosage of siRNA increases, while an exorbitant siRNA dosage will inhibit the RNAi effect. So it is crucial to formulate a dose-effect mo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580653/ https://www.ncbi.nlm.nih.gov/pubmed/31208316 http://dx.doi.org/10.1186/s12859-019-2925-z |