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Periodicity and dosage optimization of an RNAi model in eukaryotes cells

BACKGROUND: As a highly efficient and specific gene regulation technology, RNAi has broad application fields and good prospects. The effect of RNAi enhances as the dosage of siRNA increases, while an exorbitant siRNA dosage will inhibit the RNAi effect. So it is crucial to formulate a dose-effect mo...

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Detalles Bibliográficos
Autores principales: Ma, Tongle, Pei, Yongzhen, Li, Changguo, Zhu, Meixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580653/
https://www.ncbi.nlm.nih.gov/pubmed/31208316
http://dx.doi.org/10.1186/s12859-019-2925-z

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