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Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

Rationale: The contributions of diverse cell populations in the human lung to pulmonary fibrosis pathogenesis are poorly understood. Single-cell RNA sequencing can reveal changes within individual cell populations during pulmonary fibrosis that are important for disease pathogenesis. Objectives: To...

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Detalles Bibliográficos
Autores principales: Reyfman, Paul A., Walter, James M., Joshi, Nikita, Anekalla, Kishore R., McQuattie-Pimentel, Alexandra C., Chiu, Stephen, Fernandez, Ramiro, Akbarpour, Mahzad, Chen, Ching-I, Ren, Ziyou, Verma, Rohan, Abdala-Valencia, Hiam, Nam, Kiwon, Chi, Monica, Han, SeungHye, Gonzalez-Gonzalez, Francisco J., Soberanes, Saul, Watanabe, Satoshi, Williams, Kinola J. N., Flozak, Annette S., Nicholson, Trevor T., Morgan, Vince K., Winter, Deborah R., Hinchcliff, Monique, Hrusch, Cara L., Guzy, Robert D., Bonham, Catherine A., Sperling, Anne I., Bag, Remzi, Hamanaka, Robert B., Mutlu, Gökhan M., Yeldandi, Anjana V., Marshall, Stacy A., Shilatifard, Ali, Amaral, Luis A. N., Perlman, Harris, Sznajder, Jacob I., Argento, A. Christine, Gillespie, Colin T., Dematte, Jane, Jain, Manu, Singer, Benjamin D., Ridge, Karen M., Lam, Anna P., Bharat, Ankit, Bhorade, Sangeeta M., Gottardi, Cara J., Budinger, G. R. Scott, Misharin, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580683/
https://www.ncbi.nlm.nih.gov/pubmed/30554520
http://dx.doi.org/10.1164/rccm.201712-2410OC

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