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Dysregulated activation of fetal liver programme in acute liver failure

OBJECTIVE: Uncertainty about acute liver failure (ALF) pathogenesis limits therapy. We postulate that ALF results from excessive reactivation of a fetal liver programme that is induced in hepatocytes when acutely injured livers regenerate. To evaluate this hypothesis, we focused on two molecules wit...

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Detalles Bibliográficos
Autores principales:	Hyun, Jeongeun, Oh, Seh-Hoon, Premont, Richard T, Guy, Cynthia D, Berg, Carl L, Diehl, Anna Mae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580749/ https://www.ncbi.nlm.nih.gov/pubmed/30670575 http://dx.doi.org/10.1136/gutjnl-2018-317603

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