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Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage

OBJECTIVE: Liver injury impacts hepatic inflammation in part via Toll-like receptor (TLR) signalling. Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates TLR4-mediated inflammation in bone marrow (BM)-derived macrophages but its function in liver injury is unknown. Here we hypothesis...

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Detalles Bibliográficos
Autores principales:	Perugorria, Maria J, Esparza-Baquer, Aitor, Oakley, Fiona, Labiano, Ibone, Korosec, Ana, Jais, Alexander, Mann, Jelena, Tiniakos, Dina, Santos-Laso, Alvaro, Arbelaiz, Ander, Gawish, Riem, Sampedro, Ana, Fontanellas, Antonio, Hijona, Elizabeth, Jimenez-Agüero, Raul, Esterbauer, Harald, Stoiber, Dagmar, Bujanda, Luis, Banales, Jesus María, Knapp, Sylvia, Sharif, Omar, Mann, Derek A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580759/ https://www.ncbi.nlm.nih.gov/pubmed/29374630 http://dx.doi.org/10.1136/gutjnl-2017-314107

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