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How to do it: investigate exertional rhabdomyolysis (or not)

Rhabdomyolysis is the combination of symptoms (myalgia, weakness and muscle swelling) and a substantial rise in serum creatine kinase (CK) >50 000 IU/L; there are many causes, but here we specifically address exertional rhabdomyolysis. The consequences of this condition can be severe, including a...

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Autores principales: Fernandes, Peter M, Davenport, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580786/
https://www.ncbi.nlm.nih.gov/pubmed/30305378
http://dx.doi.org/10.1136/practneurol-2018-002008
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author Fernandes, Peter M
Davenport, Richard J
author_facet Fernandes, Peter M
Davenport, Richard J
author_sort Fernandes, Peter M
collection PubMed
description Rhabdomyolysis is the combination of symptoms (myalgia, weakness and muscle swelling) and a substantial rise in serum creatine kinase (CK) >50 000 IU/L; there are many causes, but here we specifically address exertional rhabdomyolysis. The consequences of this condition can be severe, including acute kidney injury and requirement for higher level care with organ support. Most patients have ‘physiological’ exertional rhabdomyolysis with no underlying disease; they do not need investigation and should be advised to return to normal activities in a graded fashion. Rarely, exertional rhabdomyolysis may be the initial presentation of underlying muscle disease, and we review how to identify this much smaller group of patients, who do require investigation.
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spelling pubmed-65807862019-07-02 How to do it: investigate exertional rhabdomyolysis (or not) Fernandes, Peter M Davenport, Richard J Pract Neurol How to Do It Rhabdomyolysis is the combination of symptoms (myalgia, weakness and muscle swelling) and a substantial rise in serum creatine kinase (CK) >50 000 IU/L; there are many causes, but here we specifically address exertional rhabdomyolysis. The consequences of this condition can be severe, including acute kidney injury and requirement for higher level care with organ support. Most patients have ‘physiological’ exertional rhabdomyolysis with no underlying disease; they do not need investigation and should be advised to return to normal activities in a graded fashion. Rarely, exertional rhabdomyolysis may be the initial presentation of underlying muscle disease, and we review how to identify this much smaller group of patients, who do require investigation. BMJ Publishing Group 2019-02 2018-10-10 /pmc/articles/PMC6580786/ /pubmed/30305378 http://dx.doi.org/10.1136/practneurol-2018-002008 Text en © Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: http://creativecommons.org/licenses/by/4.0
spellingShingle How to Do It
Fernandes, Peter M
Davenport, Richard J
How to do it: investigate exertional rhabdomyolysis (or not)
title How to do it: investigate exertional rhabdomyolysis (or not)
title_full How to do it: investigate exertional rhabdomyolysis (or not)
title_fullStr How to do it: investigate exertional rhabdomyolysis (or not)
title_full_unstemmed How to do it: investigate exertional rhabdomyolysis (or not)
title_short How to do it: investigate exertional rhabdomyolysis (or not)
title_sort how to do it: investigate exertional rhabdomyolysis (or not)
topic How to Do It
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580786/
https://www.ncbi.nlm.nih.gov/pubmed/30305378
http://dx.doi.org/10.1136/practneurol-2018-002008
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