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How to do it: investigate exertional rhabdomyolysis (or not)
Rhabdomyolysis is the combination of symptoms (myalgia, weakness and muscle swelling) and a substantial rise in serum creatine kinase (CK) >50 000 IU/L; there are many causes, but here we specifically address exertional rhabdomyolysis. The consequences of this condition can be severe, including a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580786/ https://www.ncbi.nlm.nih.gov/pubmed/30305378 http://dx.doi.org/10.1136/practneurol-2018-002008 |
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author | Fernandes, Peter M Davenport, Richard J |
author_facet | Fernandes, Peter M Davenport, Richard J |
author_sort | Fernandes, Peter M |
collection | PubMed |
description | Rhabdomyolysis is the combination of symptoms (myalgia, weakness and muscle swelling) and a substantial rise in serum creatine kinase (CK) >50 000 IU/L; there are many causes, but here we specifically address exertional rhabdomyolysis. The consequences of this condition can be severe, including acute kidney injury and requirement for higher level care with organ support. Most patients have ‘physiological’ exertional rhabdomyolysis with no underlying disease; they do not need investigation and should be advised to return to normal activities in a graded fashion. Rarely, exertional rhabdomyolysis may be the initial presentation of underlying muscle disease, and we review how to identify this much smaller group of patients, who do require investigation. |
format | Online Article Text |
id | pubmed-6580786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-65807862019-07-02 How to do it: investigate exertional rhabdomyolysis (or not) Fernandes, Peter M Davenport, Richard J Pract Neurol How to Do It Rhabdomyolysis is the combination of symptoms (myalgia, weakness and muscle swelling) and a substantial rise in serum creatine kinase (CK) >50 000 IU/L; there are many causes, but here we specifically address exertional rhabdomyolysis. The consequences of this condition can be severe, including acute kidney injury and requirement for higher level care with organ support. Most patients have ‘physiological’ exertional rhabdomyolysis with no underlying disease; they do not need investigation and should be advised to return to normal activities in a graded fashion. Rarely, exertional rhabdomyolysis may be the initial presentation of underlying muscle disease, and we review how to identify this much smaller group of patients, who do require investigation. BMJ Publishing Group 2019-02 2018-10-10 /pmc/articles/PMC6580786/ /pubmed/30305378 http://dx.doi.org/10.1136/practneurol-2018-002008 Text en © Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: http://creativecommons.org/licenses/by/4.0 |
spellingShingle | How to Do It Fernandes, Peter M Davenport, Richard J How to do it: investigate exertional rhabdomyolysis (or not) |
title | How to do it: investigate exertional rhabdomyolysis (or not) |
title_full | How to do it: investigate exertional rhabdomyolysis (or not) |
title_fullStr | How to do it: investigate exertional rhabdomyolysis (or not) |
title_full_unstemmed | How to do it: investigate exertional rhabdomyolysis (or not) |
title_short | How to do it: investigate exertional rhabdomyolysis (or not) |
title_sort | how to do it: investigate exertional rhabdomyolysis (or not) |
topic | How to Do It |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580786/ https://www.ncbi.nlm.nih.gov/pubmed/30305378 http://dx.doi.org/10.1136/practneurol-2018-002008 |
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