Cargando…

RT-QuIC: a new test for sporadic CJD

The diagnosis of sporadic Creutzfeldt-Jakob disease (CJD) can be difficult, but the real-time quaking-induced conversion (RT-QuIC) assays have made a considerable impact on its clinical diagnosis. This technique exploits the ability of the misfolded pathological form of prion protein (PrP(Sc)) found...

Descripción completa

Detalles Bibliográficos
Autor principal:	Green, Alison J E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	How to Understand It
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580883/ https://www.ncbi.nlm.nih.gov/pubmed/30282760 http://dx.doi.org/10.1136/practneurol-2018-001935

Ejemplares similares

Ring trial of 2nd generation RT‐QuIC diagnostic tests for sporadic CJD
por: Orrú, Christina D., et al.
Publicado: (2020)

Validation and Application of Skin RT-QuIC to Patients in China with Probable CJD
por: Xiao, Kang, et al.
Publicado: (2021)

Transmission of CJD from nasal brushings but not spinal fluid or RT‐QuIC product
por: Raymond, Gregory J., et al.
Publicado: (2020)

Epitope mapping of the protease resistant products of RT-QuIC does not allow the discrimination of sCJD subtypes
por: Piconi, Gabriele, et al.
Publicado: (2019)

High diagnostic value of second generation CSF RT-QuIC across the wide spectrum of CJD prions
por: Franceschini, Alessia, et al.
Publicado: (2017)

ThermoMixer-Aided Endpoint Quaking-Induced Conversion (EP-QuIC) Permits Faster Sporadic Creutzfeldt-Jakob Disease (sCJD) Identification than Real-Time Quaking-Induced Conversion (RT-QuIC)
por: Vendramelli, Robert, et al.
Publicado: (2018)

High Diagnostic Accuracy of RT-QuIC Assay in a Prospective Study of Patients with Suspected sCJD
por: Fiorini, Michele, et al.
Publicado: (2020)

Alpha‐synuclein RT‐QuIC in the CSF of patients with alpha‐synucleinopathies
por: Fairfoul, Graham, et al.
Publicado: (2016)

Detection of CWD in cervids by RT-QuIC assay of third eyelids
por: Cooper, Sarah K., et al.
Publicado: (2019)

Factors That Improve RT-QuIC Detection of Prion Seeding Activity
por: Orrú, Christina D., et al.
Publicado: (2016)

The Latest Research on RT-QuIC Assays—A Literature Review
por: Dong, Thi-Thu-Trang, et al.
Publicado: (2021)

α‐synuclein RT‐QuIC in cerebrospinal fluid of LRRK2‐linked Parkinson's disease
por: Garrido, Alicia, et al.
Publicado: (2019)

Preparation of lyophilized recombinant prion protein for TSE diagnosis by RT-QuIC
por: Hwang, Soyoun, et al.
Publicado: (2018)

RT-QuIC detection of tauopathies using full-length tau substrates
por: Tennant, Joanne M., et al.
Publicado: (2020)

In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC
por: Donadio, Vincenzo, et al.
Publicado: (2021)

Stability and Reproducibility Underscore Utility of RT-QuIC for Diagnosis of Creutzfeldt-Jakob Disease
por: Cramm, Maria, et al.
Publicado: (2015)

Extended and direct evaluation of RT‐QuIC assays for Creutzfeldt‐Jakob disease diagnosis
por: Groveman, Bradley R., et al.
Publicado: (2016)

Hofmeister Effect in RT-QuIC Seeding Activity of Chronic Wasting Disease Prions
por: Hwang, Soyoun, et al.
Publicado: (2021)

Standardization of Data Analysis for RT-QuIC-Based Detection of Chronic Wasting Disease
por: Rowden, Gage R., et al.
Publicado: (2023)

Cross-validation of the RT-QuIC assay for the antemortem detection of chronic wasting disease in elk
por: Haley, N.J., et al.
Publicado: (2020)

The functional anatomy of central auditory processing
por: Cope, Thomas E, et al.
Publicado: (2015)

Performance of αSynuclein RT-QuIC in relation to neuropathological staging of Lewy body disease
por: Hall, Sara, et al.
Publicado: (2022)

Diagnostic value of skin RT-QuIC in Parkinson’s disease: a two-laboratory study
por: Kuzkina, Anastasia, et al.
Publicado: (2021)

α‐Synuclein RT‐QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies
por: Bongianni, Matilde, et al.
Publicado: (2019)

Use of different RT-QuIC substrates for detecting CWD prions in the brain of Norwegian cervids
por: Bistaffa, Edoardo, et al.
Publicado: (2019)

Second-Generation RT-QuIC Assay for the Diagnosis of Creutzfeldt-Jakob Disease Patients in Brazil
por: Barbosa, Breno José Alencar Pires, et al.
Publicado: (2020)

Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies
por: Rossi, Marcello, et al.
Publicado: (2020)

Magnetoencephalography
por: Proudfoot, Malcolm, et al.
Publicado: (2014)

Whole-genome sequencing
por: Morris, Huw R, et al.
Publicado: (2021)

Sporadic Creutzfeldt-Jakob disease: Real-Time Quaking-Induced Conversion (RT-QuIC) assay represents a major diagnostic advance
por: Cazzaniga, Federico Angelo, et al.
Publicado: (2021)

Source genotype influence on cross species transmission of transmissible spongiform encephalopathies evaluated by RT-QuIC
por: Hwang, Soyoun, et al.
Publicado: (2018)

Rapid and Sensitive RT-QuIC Detection of Human Creutzfeldt-Jakob Disease Using Cerebrospinal Fluid
por: Orrú, Christina D., et al.
Publicado: (2015)

Correction to: Ultrasensitive RT-QuIC assay with high sensitivity and specificity for Lewy body-associated synucleinopathies
por: Rossi, Marcello, et al.
Publicado: (2020)

Creutzfeldt–Jakob disease in pregnancy: the use of modified RT-QuIC to determine infectivity in placental tissues
por: Luk, Collin C., et al.
Publicado: (2021)

RT-QuIC detection of CWD prion seeding activity in white-tailed deer muscle tissues
por: Li, Manci, et al.
Publicado: (2021)

RT‐QuIC Detection of Pathological α‐Synuclein in Skin Punches of Patients with Lewy Body Disease
por: Mammana, Angela, et al.
Publicado: (2021)

RT-QuIC and Related Assays for Detecting and Quantifying Prion-like Pathological Seeds of α-Synuclein
por: Srivastava, Ankit, et al.
Publicado: (2022)

Identification of α-Synuclein Proaggregator: Rapid Synthesis and Streamlining RT-QuIC Assays in Parkinson’s Disease
por: Takada, Fumito, et al.
Publicado: (2022)

Salivary α‐Synuclein RT‐QuIC Correlates with Disease Severity in de novo Parkinson's Disease
por: Vivacqua, Giorgio, et al.
Publicado: (2022)

Progression of chronic wasting disease in white-tailed deer analyzed by serial biopsy RT-QuIC and immunohistochemistry
por: Henderson, Davin M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_er1d6njdecsmiubmtfe87qqanr