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Quantitative Proteomic Analysis Reveals the Sites Related to Acetylation and Mechanism of ACY-1215 in Acute Liver Failure Mice

Background: ACY-1215 is a well-known selective histone deacetylase 6 (HDAC6) inhibitor, and it has been considered as a potential therapeutic drug in inflammatory diseases, including acute liver failure (ALF). However, little is known about the impact of ACY-1215 treatment on histone lysine acetylat...

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Detalles Bibliográficos
Autores principales: Zhang, Wen-bin, Zhang, Hai-yue, Wang, Yao, Jiao, Fang-zhou, Wang, Lu-wen, Gong, Zuo-jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581020/
https://www.ncbi.nlm.nih.gov/pubmed/31244662
http://dx.doi.org/10.3389/fphar.2019.00653