Integrative network and brain expression analysis reveals mechanistic modules in ataxia

BACKGROUND: Genetic forms of ataxia are a heterogenous group of degenerative diseases of the cerebellum. Many causative genes have been identified. We aimed to systematically investigate these genes to better understand ataxia pathophysiology. METHODS: A manually curated catalogue of 71 genes involv...

Descripción completa

Detalles Bibliográficos
Autores principales: Eidhof, Ilse, van de Warrenburg, Bart P, Schenck, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Neurogenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581079/
https://www.ncbi.nlm.nih.gov/pubmed/30591515
http://dx.doi.org/10.1136/jmedgenet-2018-105703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581079/
https://www.ncbi.nlm.nih.gov/pubmed/30591515
http://dx.doi.org/10.1136/jmedgenet-2018-105703

Ejemplares similares