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Integrative network and brain expression analysis reveals mechanistic modules in ataxia

BACKGROUND: Genetic forms of ataxia are a heterogenous group of degenerative diseases of the cerebellum. Many causative genes have been identified. We aimed to systematically investigate these genes to better understand ataxia pathophysiology. METHODS: A manually curated catalogue of 71 genes involv...

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Detalles Bibliográficos
Autores principales:	Eidhof, Ilse, van de Warrenburg, Bart P, Schenck, Annette
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Neurogenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581079/ https://www.ncbi.nlm.nih.gov/pubmed/30591515 http://dx.doi.org/10.1136/jmedgenet-2018-105703

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