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Experimental platforms to study blast injury

Injuries sustained due to attacks from explosive weapons are multiple in number, complex in nature, and not well characterised. Blast may cause damage to the human body by the direct effect of overpressure, penetration by highly energised fragments, and blunt trauma by violent displacements of the b...

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Autores principales: Nguyen, Thuy-Tien, Pearce, A P, Carpanen, D, Sory, D, Grigoriadis, G, Newell, N, Clasper, J, Bull, A, Proud, W G, Masouros, S D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581094/
https://www.ncbi.nlm.nih.gov/pubmed/29794172
http://dx.doi.org/10.1136/jramc-2018-000966
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author Nguyen, Thuy-Tien
Pearce, A P
Carpanen, D
Sory, D
Grigoriadis, G
Newell, N
Clasper, J
Bull, A
Proud, W G
Masouros, S D
author_facet Nguyen, Thuy-Tien
Pearce, A P
Carpanen, D
Sory, D
Grigoriadis, G
Newell, N
Clasper, J
Bull, A
Proud, W G
Masouros, S D
author_sort Nguyen, Thuy-Tien
collection PubMed
description Injuries sustained due to attacks from explosive weapons are multiple in number, complex in nature, and not well characterised. Blast may cause damage to the human body by the direct effect of overpressure, penetration by highly energised fragments, and blunt trauma by violent displacements of the body. The ability to reproduce the injuries of such insults in a well-controlled fashion is essential in order to understand fully the unique mechanism by which they occur, and design better treatment and protection strategies to alleviate the resulting poor long-term outcomes. This paper reports a range of experimental platforms that have been developed for different blast injury models, their working mechanism, and main applications. These platforms include the shock tube, split-Hopkinson bars, the gas gun, drop towers and bespoke underbody blast simulators.
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spelling pubmed-65810942019-07-05 Experimental platforms to study blast injury Nguyen, Thuy-Tien Pearce, A P Carpanen, D Sory, D Grigoriadis, G Newell, N Clasper, J Bull, A Proud, W G Masouros, S D J R Army Med Corps Original Article Injuries sustained due to attacks from explosive weapons are multiple in number, complex in nature, and not well characterised. Blast may cause damage to the human body by the direct effect of overpressure, penetration by highly energised fragments, and blunt trauma by violent displacements of the body. The ability to reproduce the injuries of such insults in a well-controlled fashion is essential in order to understand fully the unique mechanism by which they occur, and design better treatment and protection strategies to alleviate the resulting poor long-term outcomes. This paper reports a range of experimental platforms that have been developed for different blast injury models, their working mechanism, and main applications. These platforms include the shock tube, split-Hopkinson bars, the gas gun, drop towers and bespoke underbody blast simulators. BMJ Publishing Group 2019-02 2018-05-24 /pmc/articles/PMC6581094/ /pubmed/29794172 http://dx.doi.org/10.1136/jramc-2018-000966 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2019. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
spellingShingle Original Article
Nguyen, Thuy-Tien
Pearce, A P
Carpanen, D
Sory, D
Grigoriadis, G
Newell, N
Clasper, J
Bull, A
Proud, W G
Masouros, S D
Experimental platforms to study blast injury
title Experimental platforms to study blast injury
title_full Experimental platforms to study blast injury
title_fullStr Experimental platforms to study blast injury
title_full_unstemmed Experimental platforms to study blast injury
title_short Experimental platforms to study blast injury
title_sort experimental platforms to study blast injury
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581094/
https://www.ncbi.nlm.nih.gov/pubmed/29794172
http://dx.doi.org/10.1136/jramc-2018-000966
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