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Experimental platforms to study blast injury
Injuries sustained due to attacks from explosive weapons are multiple in number, complex in nature, and not well characterised. Blast may cause damage to the human body by the direct effect of overpressure, penetration by highly energised fragments, and blunt trauma by violent displacements of the b...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581094/ https://www.ncbi.nlm.nih.gov/pubmed/29794172 http://dx.doi.org/10.1136/jramc-2018-000966 |
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author | Nguyen, Thuy-Tien Pearce, A P Carpanen, D Sory, D Grigoriadis, G Newell, N Clasper, J Bull, A Proud, W G Masouros, S D |
author_facet | Nguyen, Thuy-Tien Pearce, A P Carpanen, D Sory, D Grigoriadis, G Newell, N Clasper, J Bull, A Proud, W G Masouros, S D |
author_sort | Nguyen, Thuy-Tien |
collection | PubMed |
description | Injuries sustained due to attacks from explosive weapons are multiple in number, complex in nature, and not well characterised. Blast may cause damage to the human body by the direct effect of overpressure, penetration by highly energised fragments, and blunt trauma by violent displacements of the body. The ability to reproduce the injuries of such insults in a well-controlled fashion is essential in order to understand fully the unique mechanism by which they occur, and design better treatment and protection strategies to alleviate the resulting poor long-term outcomes. This paper reports a range of experimental platforms that have been developed for different blast injury models, their working mechanism, and main applications. These platforms include the shock tube, split-Hopkinson bars, the gas gun, drop towers and bespoke underbody blast simulators. |
format | Online Article Text |
id | pubmed-6581094 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-65810942019-07-05 Experimental platforms to study blast injury Nguyen, Thuy-Tien Pearce, A P Carpanen, D Sory, D Grigoriadis, G Newell, N Clasper, J Bull, A Proud, W G Masouros, S D J R Army Med Corps Original Article Injuries sustained due to attacks from explosive weapons are multiple in number, complex in nature, and not well characterised. Blast may cause damage to the human body by the direct effect of overpressure, penetration by highly energised fragments, and blunt trauma by violent displacements of the body. The ability to reproduce the injuries of such insults in a well-controlled fashion is essential in order to understand fully the unique mechanism by which they occur, and design better treatment and protection strategies to alleviate the resulting poor long-term outcomes. This paper reports a range of experimental platforms that have been developed for different blast injury models, their working mechanism, and main applications. These platforms include the shock tube, split-Hopkinson bars, the gas gun, drop towers and bespoke underbody blast simulators. BMJ Publishing Group 2019-02 2018-05-24 /pmc/articles/PMC6581094/ /pubmed/29794172 http://dx.doi.org/10.1136/jramc-2018-000966 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2019. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Original Article Nguyen, Thuy-Tien Pearce, A P Carpanen, D Sory, D Grigoriadis, G Newell, N Clasper, J Bull, A Proud, W G Masouros, S D Experimental platforms to study blast injury |
title | Experimental platforms to study blast injury |
title_full | Experimental platforms to study blast injury |
title_fullStr | Experimental platforms to study blast injury |
title_full_unstemmed | Experimental platforms to study blast injury |
title_short | Experimental platforms to study blast injury |
title_sort | experimental platforms to study blast injury |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581094/ https://www.ncbi.nlm.nih.gov/pubmed/29794172 http://dx.doi.org/10.1136/jramc-2018-000966 |
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