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The breadth of HIV-1 neutralizing antibodies depends on the conservation of key sites in their epitopes
Developing HIV-1 vaccines that trigger broadly neutralizing antibodies (bnAbs) is a priority as bnAbs are considered key to elicitation of a protective immune response. To investigate whether the breadth of a neutralizing antibody (nAb) depended on the conservation of its epitope among circulating v...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581281/ https://www.ncbi.nlm.nih.gov/pubmed/31170145 http://dx.doi.org/10.1371/journal.pcbi.1007056 |