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The breadth of HIV-1 neutralizing antibodies depends on the conservation of key sites in their epitopes

Developing HIV-1 vaccines that trigger broadly neutralizing antibodies (bnAbs) is a priority as bnAbs are considered key to elicitation of a protective immune response. To investigate whether the breadth of a neutralizing antibody (nAb) depended on the conservation of its epitope among circulating v...

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Detalles Bibliográficos
Autores principales:	Bai, Hongjun, Li, Yifan, Michael, Nelson L., Robb, Merlin L., Rolland, Morgane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581281/ https://www.ncbi.nlm.nih.gov/pubmed/31170145 http://dx.doi.org/10.1371/journal.pcbi.1007056

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