Calcium Channel Blocker Overdose Treated with Calcium Resulting in Pancreatitis: A Case Report

Calcium channel blockers (CCBs) are a mainstay for the treatment of hypertension. Here we report a case of a male who after intentionally ingesting amlodipine presented with overdose symptomology. His QTc (corrected QT) was 525 ms (millisecond) on admission, he was treated with calcium intravenous i...

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Detalles Bibliográficos
Autores principales: Khan, Salman, Norville, Kim J, Khan, Imran, Siddiqui, Faraz, Karki, Apurwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581410/
https://www.ncbi.nlm.nih.gov/pubmed/31259111
http://dx.doi.org/10.7759/cureus.4493
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author Khan, Salman
Norville, Kim J
Khan, Imran
Siddiqui, Faraz
Karki, Apurwa
author_facet Khan, Salman
Norville, Kim J
Khan, Imran
Siddiqui, Faraz
Karki, Apurwa
author_sort Khan, Salman
collection PubMed
description Calcium channel blockers (CCBs) are a mainstay for the treatment of hypertension. Here we report a case of a male who after intentionally ingesting amlodipine presented with overdose symptomology. His QTc (corrected QT) was 525 ms (millisecond) on admission, he was treated with calcium intravenous infusion and subsequently his QTc narrowed to 393 ms, but he also developed iatrogenic pancreatitis. His serum calcium levels were not checked during the infusion. He was treated with supportive care, which led to the normalization of serum calcium levels and a favorable outcome. Further studies are required regarding how frequently calcium levels should be checked during infusions.
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spelling pubmed-65814102019-06-28 Calcium Channel Blocker Overdose Treated with Calcium Resulting in Pancreatitis: A Case Report Khan, Salman Norville, Kim J Khan, Imran Siddiqui, Faraz Karki, Apurwa Cureus Internal Medicine Calcium channel blockers (CCBs) are a mainstay for the treatment of hypertension. Here we report a case of a male who after intentionally ingesting amlodipine presented with overdose symptomology. His QTc (corrected QT) was 525 ms (millisecond) on admission, he was treated with calcium intravenous infusion and subsequently his QTc narrowed to 393 ms, but he also developed iatrogenic pancreatitis. His serum calcium levels were not checked during the infusion. He was treated with supportive care, which led to the normalization of serum calcium levels and a favorable outcome. Further studies are required regarding how frequently calcium levels should be checked during infusions. Cureus 2019-04-18 /pmc/articles/PMC6581410/ /pubmed/31259111 http://dx.doi.org/10.7759/cureus.4493 Text en Copyright © 2019, Khan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Khan, Salman
Norville, Kim J
Khan, Imran
Siddiqui, Faraz
Karki, Apurwa
Calcium Channel Blocker Overdose Treated with Calcium Resulting in Pancreatitis: A Case Report
title Calcium Channel Blocker Overdose Treated with Calcium Resulting in Pancreatitis: A Case Report
title_full Calcium Channel Blocker Overdose Treated with Calcium Resulting in Pancreatitis: A Case Report
title_fullStr Calcium Channel Blocker Overdose Treated with Calcium Resulting in Pancreatitis: A Case Report
title_full_unstemmed Calcium Channel Blocker Overdose Treated with Calcium Resulting in Pancreatitis: A Case Report
title_short Calcium Channel Blocker Overdose Treated with Calcium Resulting in Pancreatitis: A Case Report
title_sort calcium channel blocker overdose treated with calcium resulting in pancreatitis: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581410/
https://www.ncbi.nlm.nih.gov/pubmed/31259111
http://dx.doi.org/10.7759/cureus.4493
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