Impact of Host DNA and Sequencing Depth on the Taxonomic Resolution of Whole Metagenome Sequencing for Microbiome Analysis

The amount of host DNA poses a major challenge to metagenome analysis. However, there is no guidance on the levels of host DNA, nor on the depth of sequencing needed to acquire meaningful information from whole metagenome sequencing (WMS). Here, we evaluated the impact of a wide range of amounts of...

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Detalles Bibliográficos
Autores principales: Pereira-Marques, Joana, Hout, Anne, Ferreira, Rui M., Weber, Michiel, Pinto-Ribeiro, Ines, van Doorn, Leen-Jan, Knetsch, Cornelis Willem, Figueiredo, Ceu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581681/
https://www.ncbi.nlm.nih.gov/pubmed/31244801
http://dx.doi.org/10.3389/fmicb.2019.01277

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