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Gradual in vitro Evolution of Cefepime Resistance in an ST131 Escherichia coli Strain Expressing a Plasmid-Encoded CMY-2 β-Lactamase

BACKGROUND: In a previous report, a clinical ST131 Escherichia coli isolate (Ec-1),producing a plasmid-encoded AmpC β-lactamase CMY-2, evolved in vivo under cefepime (FEP) treatment to the FEP-resistant Ec-2 strain expressing an extended-spectrum β-lactamase CMY-33. To compare factors responsible fo...

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Detalles Bibliográficos
Autores principales:	Donà, Valentina, Scheidegger, Maximilian, Pires, João, Furrer, Hansjakob, Atkinson, Andrew, Babouee Flury, Baharak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581752/ https://www.ncbi.nlm.nih.gov/pubmed/31244817 http://dx.doi.org/10.3389/fmicb.2019.01311

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