Cargando…

Highly sensitive droplet digital PCR method for detection of residual undifferentiated cells in cardiomyocytes derived from human pluripotent stem cells

Human pluripotent stem cells (hPSCs), such as human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), are leading candidate cells as raw materials for cell therapy products, because of their capacity for pluripotent differentiation and unlimited self-renewal. hPSC-deriv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kuroda, Takuya, Yasuda, Satoshi, Matsuyama, Satoko, Tano, Keiko, Kusakawa, Shinji, Sawa, Yoshiki, Kawamata, Shin, Sato, Yoji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Society for Regenerative Medicine 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581767/ https://www.ncbi.nlm.nih.gov/pubmed/31245455 http://dx.doi.org/10.1016/j.reth.2015.08.001

Ejemplares similares

SALL3 expression balance underlies lineage biases in human induced pluripotent stem cell differentiation
por: Kuroda, Takuya, et al.
Publicado: (2019)

Development of selective cytotoxic viral vectors for concentration of undifferentiated cells in cardiomyocytes derived from human induced pluripotent stem cells
por: Kono, Ken, et al.
Publicado: (2019)

Highly Sensitive In Vitro Methods for Detection of Residual Undifferentiated Cells in Retinal Pigment Epithelial Cells Derived from Human iPS Cells
por: Kuroda, Takuya, et al.
Publicado: (2012)

A Novel In Vitro Method for Detecting Undifferentiated Human Pluripotent Stem Cells as Impurities in Cell Therapy Products Using a Highly Efficient Culture System
por: Tano, Keiko, et al.
Publicado: (2014)

Identification of a Gene Encoding Slow Skeletal Muscle Troponin T as a Novel Marker for Immortalization of Retinal Pigment Epithelial Cells
por: Kuroda, Takuya, et al.
Publicado: (2017)

Tumorigenicity-associated characteristics of human iPS cell lines
por: Yasuda, Satoshi, et al.
Publicado: (2018)

Ultra-sensitive detection of tumorigenic cellular impurities in human cell-processed therapeutic products by digital analysis of soft agar colony formation
por: Kusakawa, Shinji, et al.
Publicado: (2015)

A selective cytotoxic adenovirus vector for concentration of pluripotent stem cells in human pluripotent stem cell-derived neural progenitor cells
por: Hirai, Takamasa, et al.
Publicado: (2021)

Salicylic diamines selectively eliminate residual undifferentiated cells from pluripotent stem cell-derived cardiomyocyte preparations
por: Burkert, Karsten, et al.
Publicado: (2021)

Characterization of in vivo tumorigenicity tests using severe immunodeficient NOD/Shi-scid IL2Rγ(null) mice for detection of tumorigenic cellular impurities in human cell-processed therapeutic products
por: Kusakawa, Shinji, et al.
Publicado: (2015)

Single-Cell RNA-Seq Reveals LRRC75A-Expressing Cell Population Involved in VEGF Secretion of Multipotent Mesenchymal Stromal/Stem Cells Under Ischemia
por: Miura, Takumi, et al.
Publicado: (2023)

CXCL4/PF4 is a predictive biomarker of cardiac differentiation potential of human induced pluripotent stem cells
por: Ohashi, Fumiya, et al.
Publicado: (2019)

Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model
por: Nakamura, Yuki, et al.
Publicado: (2019)

Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Soluble Factors from Human Mesenchymal Stem Cells
por: Yoshida, Shohei, et al.
Publicado: (2018)

A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of autologous human induced pluripotent stem(-like) cells()
por: Hayakawa, Takao, et al.
Publicado: (2015)

A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of allogeneic human induced pluripotent stem(-Like) cells()
por: Hayakawa, Takao, et al.
Publicado: (2015)

Syngeneic Mesenchymal Stem Cells Reduce Immune Rejection After Induced Pluripotent Stem Cell-Derived Allogeneic Cardiomyocyte Transplantation
por: Yoshida, Shohei, et al.
Publicado: (2020)

In vitro methods to ensure absence of residual undifferentiated human induced pluripotent stem cells intermingled in induced nephron progenitor cells
por: Tsujimoto, Hiraku, et al.
Publicado: (2022)

Estimating residual undifferentiated cells in human chemically induced pluripotent stem cell derived islets using lncRNA as biomarkers
por: Wu, Yandan, et al.
Publicado: (2023)

Human induced pluripotent stem cell-derived three-dimensional cardiomyocyte tissues ameliorate the rat ischemic myocardium by remodeling the extracellular matrix and cardiac protein phenotype
por: Yokoyama, Junya, et al.
Publicado: (2021)

N-Glycans: Phenotypic Homology and Structural Differences between Myocardial Cells and Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Kawamura, Takuji, et al.
Publicado: (2014)

Publisher Correction: Syngeneic Mesenchymal Stem Cells Reduce Immune Rejection After Induced Pluripotent Stem Cell-Derived Allogeneic Cardiomyocyte Transplantation
por: Yoshida, Shohei, et al.
Publicado: (2020)

Pivotal Role of Non-cardiomyocytes in Electromechanical and Therapeutic Potential of Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissue
por: Iseoka, Hiroko, et al.
Publicado: (2018)

Case report: Transplantation of human induced pluripotent stem cell-derived cardiomyocyte patches for ischemic cardiomyopathy
por: Miyagawa, Shigeru, et al.
Publicado: (2022)

Chimerism through the activation of invariant natural killer T cells prolongs graft survival after transplantation of induced pluripotent stem cell–derived allogeneic cardiomyocytes
por: Yoshida, Shohei, et al.
Publicado: (2022)

Improving the differentiation potential of pluripotent stem cells by optimizing culture conditions
por: Yamamoto, Takako, et al.
Publicado: (2022)

Expression of Chrna9 is regulated by Tbx3 in undifferentiated pluripotent stem cells
por: Yazawa, Takashi, et al.
Publicado: (2023)

Decreased YAP activity reduces proliferative ability in human induced pluripotent stem cell of duchenne muscular dystrophy derived cardiomyocytes
por: Yasutake, Hideki, et al.
Publicado: (2021)

Phenotypic recapitulation and correction of desmoglein-2-deficient cardiomyopathy using human-induced pluripotent stem cell-derived cardiomyocytes
por: Shiba, Mikio, et al.
Publicado: (2021)

Sialyl-lactotetra, a Novel Cell Surface Marker of Undifferentiated Human Pluripotent Stem Cells
por: Barone, Angela, et al.
Publicado: (2014)

Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies
por: Chour, Tony, et al.
Publicado: (2021)

Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application
por: Ito, Emiko, et al.
Publicado: (2019)

Safety confirmation of induced pluripotent stem cell-derived cardiomyocyte patch transplantation for ischemic cardiomyopathy: first three case reports
por: Kawamura, Takuji, et al.
Publicado: (2023)

Intramyocardial Transplantation of Undifferentiated Rat Induced Pluripotent Stem Cells Causes Tumorigenesis in the Heart
por: Zhang, Yuzhen, et al.
Publicado: (2011)

MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells
por: Parr, Callum J. C., et al.
Publicado: (2016)

Plasma-activated medium selectively eliminates undifferentiated human induced pluripotent stem cells
por: Matsumoto, Ryo, et al.
Publicado: (2016)

Transplantation of Human-induced Pluripotent Stem Cell-derived Cardiomyocytes Is Superior to Somatic Stem Cell Therapy for Restoring Cardiac Function and Oxygen Consumption in a Porcine Model of Myocardial Infarction
por: Ishida, Masaru, et al.
Publicado: (2019)

Human-Induced Pluripotent Stem Cell–Derived Cardiomyocyte Model for TNNT2 Δ160E-Induced Cardiomyopathy
por: Kondo, Takumi, et al.
Publicado: (2022)

Co-culture of induced pluripotent stem cells with cardiomyocytes is sufficient to promote their differentiation into cardiomyocytes
por: Chu, Axel J., et al.
Publicado: (2020)

Cardiomyocytes Derived from MHC-Homozygous Induced Pluripotent Stem Cells Exhibit Reduced Allogeneic Immunogenicity in MHC-Matched Non-human Primates
por: Kawamura, Takuji, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_pah5a6onr0kvquiv3n0vegsmpg