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Identification of rare variants of allergic rhinitis based on whole genome sequencing and gene expression profiling: A preliminary investigation in four families

BACKGROUND: Despite the success of genome-wide association studies for allergic rhinitis (AR), no definitive causal variants have been identified, and a substantial portion of the heritability of the disease is yet to be discovered. METHODS: Four families, each with at least 1 parent and one child s...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Li, Jingyun, Zhao, Yali, Wang, Chengshuo, Zhang, Luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581771/
https://www.ncbi.nlm.nih.gov/pubmed/31236190
http://dx.doi.org/10.1016/j.waojou.2019.100038