Cargando…

Electrophysiological properties of iPS cell-derived cardiomyocytes from a patient with long QT syndrome type 1 harboring the novel mutation M437V of KCNQ1

INTRODUCTION: Long QT syndrome type 1 (LQT1) is caused by mutations in KCNQ1 coding slowly-activating delayed-rectifier K(+) channels. We identified the novel missense mutation M437V of KCNQ1 in a LQT1 patient. Here, we employed iPS cell (iPSC)-derived cardiomyocytes to investigate electrophysiologi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sogo, Tatsufumi, Morikawa, Kumi, Kurata, Yasutaka, Li, Peili, Ichinose, Takafumi, Yuasa, Shinsuke, Nozaki, Daizou, Miake, Junichiro, Ninomiya, Haruaki, Shimizu, Wataru, Fukuda, Keiichi, Yamamoto, Kazuhiro, Shirayoshi, Yasuaki, Hisatome, Ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Society for Regenerative Medicine 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581809/ https://www.ncbi.nlm.nih.gov/pubmed/31245483 http://dx.doi.org/10.1016/j.reth.2015.12.001

Ejemplares similares

Inhibitory effects of class I antiarrhythmic agents on Na(+) and Ca(2+) currents of human iPS cell-derived cardiomyocytes
por: Yonemizu, Sayaka, et al.
Publicado: (2019)

SHOX2 refines the identification of human sinoatrial nodal cell population in the in vitro cardiac differentiation
por: Wakimizu, Takayuki, et al.
Publicado: (2022)

Molecular mechanisms underlying the pilsicainide-induced stabilization of hERG proteins in transfected mammalian cells
por: Onohara, Takeshi, et al.
Publicado: (2017)

Kv1.5 channel mediates monosodium urate-induced activation of NLRP3 inflammasome in macrophages and arrhythmogenic effects of urate on cardiomyocytes
por: Li, Peili, et al.
Publicado: (2022)

Characterization of the novel mutant A78T-HERG from a long QT syndrome type 2 patient: Instability of the mutant protein and stabilization by heat shock factor 1
por: Kondo, Takehito, et al.
Publicado: (2016)

Pretreatment with an angiotensin II receptor blocker abolished ameliorating actions of adipose-derived stem cell sheets on cardiac dysfunction and remodeling after myocardial infarction
por: Yamamoto, Kenshiro, et al.
Publicado: (2018)

Evidence for Urate Uptake Through Monocarboxylate Transporter 9 Expressed in Mammalian Cells and Its Enhancement by Heat Shock
por: Otani, Naoyuki, et al.
Publicado: (2020)

Deep learning‐based identification of sinoatrial node‐like pacemaker cells from SHOX2/HCN4 double‐positive cells differentiated from human iPS cells
por: Wakimizu, Takayuki, et al.
Publicado: (2023)

Novel dual-reporter transgenic rodents enable cell tracking in animal models of stem cell transplantation
por: Morikawa, Kumi, et al.
Publicado: (2019)

Hyperuricemia as a Risk Factor for Atrial Fibrillation Due to Soluble and Crystalized Uric Acid
por: Taufiq, Fikri, et al.
Publicado: (2019)

Impact of Hyper- and Hypo-Uricemia on Kidney Function
por: Miake, Junichiro, et al.
Publicado: (2023)

Effects of Conditioned Medium of Adipose-Derived Stem Cells Exposed to Platelet-Rich Plasma on the Expression of Endothelial Nitric Oxide Synthase and Angiogenesis by Endothelial Cells
por: Morita, Maki, et al.
Publicado: (2023)

KCNQ1-deficient and KCNQ1-mutant human embryonic stem cell-derived cardiomyocytes for modeling QT prolongation
por: Song, Yuanxiu, et al.
Publicado: (2022)

A novel variant in KCNQ1 associated with short QT syndrome
por: Schneider, Kristin, et al.
Publicado: (2021)

Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)-1 stabilizes K(v)1.5 channels in HL-1 cells
por: Ting, YK, et al.
Publicado: (2011)

In silico investigation of a KCNQ1 mutation associated with short QT syndrome
por: Adeniran, Ismail, et al.
Publicado: (2017)

Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels
por: Zou, Xinle, et al.
Publicado: (2022)

SAT437 Immunotherapy Induced Pituitary Apoplexy
por: Uddin, Ashraf, et al.
Publicado: (2023)

Atypical long QT syndrome phenotype in heterozygous/homozygous KCNQ1 Ala590Thr
por: Smith, Justin D., et al.
Publicado: (2017)

ZAC, LIT1 (KCNQ1OT1) and p57(KIP2) (CDKN1C) are in an imprinted gene network that may play a role in Beckwith–Wiedemann syndrome
por: Arima, Takahiro, et al.
Publicado: (2005)

Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations
por: Huang, Hui, et al.
Publicado: (2018)

CCNP Voice CVoice 642-437: quick reference
por: Sauer, Toby, et al.
Publicado: (2011)

SUN-437 Central Adrenal Insufficiency Unmasked by Pregnancy
por: Araque, Katherine, et al.
Publicado: (2019)

MON-437 False Positive I-131 Uptake
por: Yadav, Pavan Rajendra, et al.
Publicado: (2020)

Antiviral Activity of CD437 Against Mumps Virus
por: Kato, Fumihiro, et al.
Publicado: (2021)

Correction to Lancet Neurol 2021; 20: 437–47
Publicado: (2021)

MHY1485 enhances X-irradiation-induced apoptosis and senescence in tumor cells
por: Sun, Lue, et al.
Publicado: (2021)

A Long QT Mutation Substitutes Cholesterol for Phosphatidylinositol-4,5-Bisphosphate in KCNQ1 Channel Regulation
por: Coyan, Fabien C., et al.
Publicado: (2014)

Identification of a Novel KCNQ1 Frameshift Mutation and Review of the Literature among Iranian Long QT Families
por: Amirian, Azam, et al.
Publicado: (2019)

Association of the P441L KCNQ1 variant with severity of long QT syndrome and risk of cardiac events
por: Lu, Haoyang, et al.
Publicado: (2022)

In vivo KCNQ1-suppression-replacement gene therapy in transgenic rabbits with type 1 long QT syndrome
por: Giammarino, L, et al.
Publicado: (2023)

A novel stop-gain pathogenic variant in the KCNQ1 gene causing long QT syndrome 1
por: Kalayinia, Samira, et al.
Publicado: (2023)

437. Asymptomatic Healthcare Worker COVID-19 Testing Program
por: Horton, Lucy E, et al.
Publicado: (2020)

THU437 Oral Ulcers As A Clue To Bone Fragility
por: Sridhar, Sushrutha, et al.
Publicado: (2023)

KCNQ2 and KCNQ5 form heteromeric channels independent of KCNQ3
por: Soh, Heun, et al.
Publicado: (2022)

Sudden Death Associated with QT Interval Prolongation and KCNQ1 Gene Mutation in a Family of English Springer Spaniels
por: Ware, W.A., et al.
Publicado: (2015)

The Role of KCNQ1 Mutations and Maternal Beta Blocker Use During Pregnancy in the Growth of Children With Long QT Syndrome
por: Huttunen, Heta, et al.
Publicado: (2018)

Human Atrial Arrhythmogenesis and Sinus Bradycardia in KCNQ1-Linked Short QT Syndrome: Insights From Computational Modelling
por: Whittaker, Dominic G., et al.
Publicado: (2018)

Clinical Implications and Gender Differences of KCNQ1 p.Gly168Arg Pathogenic Variant in Long QT Syndrome
por: Lorca, Rebeca, et al.
Publicado: (2020)

Novel combinations of variations in KCNQ1 were associated with patients with long QT syndrome or Jervell and Lange-Nielsen syndrome
por: Zhao, Nongnong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nj95j4vmgieuuebapq19qa344n