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Cell therapy for spinal cord injury using induced pluripotent stem cells
For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society for Regenerative Medicine
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581851/ https://www.ncbi.nlm.nih.gov/pubmed/31245451 http://dx.doi.org/10.1016/j.reth.2019.05.006 |
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author | Nagoshi, Narihito Tsuji, Osahiko Nakamura, Masaya Okano, Hideyuki |
author_facet | Nagoshi, Narihito Tsuji, Osahiko Nakamura, Masaya Okano, Hideyuki |
author_sort | Nagoshi, Narihito |
collection | PubMed |
description | For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications. |
format | Online Article Text |
id | pubmed-6581851 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Japanese Society for Regenerative Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-65818512019-06-26 Cell therapy for spinal cord injury using induced pluripotent stem cells Nagoshi, Narihito Tsuji, Osahiko Nakamura, Masaya Okano, Hideyuki Regen Ther Review Article For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications. Japanese Society for Regenerative Medicine 2019-06-13 /pmc/articles/PMC6581851/ /pubmed/31245451 http://dx.doi.org/10.1016/j.reth.2019.05.006 Text en © 2019 The Japanese Society for Regenerative Medicine. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Nagoshi, Narihito Tsuji, Osahiko Nakamura, Masaya Okano, Hideyuki Cell therapy for spinal cord injury using induced pluripotent stem cells |
title | Cell therapy for spinal cord injury using induced pluripotent stem cells |
title_full | Cell therapy for spinal cord injury using induced pluripotent stem cells |
title_fullStr | Cell therapy for spinal cord injury using induced pluripotent stem cells |
title_full_unstemmed | Cell therapy for spinal cord injury using induced pluripotent stem cells |
title_short | Cell therapy for spinal cord injury using induced pluripotent stem cells |
title_sort | cell therapy for spinal cord injury using induced pluripotent stem cells |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581851/ https://www.ncbi.nlm.nih.gov/pubmed/31245451 http://dx.doi.org/10.1016/j.reth.2019.05.006 |
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