Pulmonary Iron Limitation Induced by Exogenous Type I IFN Protects Mice from Cryptococcus gattii Independently of T Cells

Cryptococcus neoformans causes deadly mycosis primarily in AIDS patients, whereas Cryptococcus gattii infects mostly non-HIV patients, even in regions with high burdens of HIV/AIDS and an established environmental presence of C. gattii. As HIV induces type I IFN (t1IFN), we hypothesized that t1IFN w...

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Detalles Bibliográficos
Autores principales: Davis, Michael J., Moyer, Shannon, Hoke, Elizabeth S., Sionov, Edward, Mayer-Barber, Katrin D., Barber, Dan L., Cai, Hongyi, Jenkins, Lisa, Walter, Peter J., Chang, Yun C., Kwon-Chung, Kyung J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581853/
https://www.ncbi.nlm.nih.gov/pubmed/31213551
http://dx.doi.org/10.1128/mBio.00799-19

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