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The Syndrome We Agreed to Call Bronchiolitis

We are ignoring evidence suggesting that the diagnosis of bronchiolitis encompasses several diseases with distinct underlying mechanisms, considerable heterogeneity in treatment responses, and ultimately different therapeutic targets. Understanding this heterogeneity may be the only way to deliver a...

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Detalles Bibliográficos
Autores principales: Polack, Fernando P, Stein, Renato T, Custovic, Adnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581899/
https://www.ncbi.nlm.nih.gov/pubmed/30783666
http://dx.doi.org/10.1093/infdis/jiz082
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author Polack, Fernando P
Stein, Renato T
Custovic, Adnan
author_facet Polack, Fernando P
Stein, Renato T
Custovic, Adnan
author_sort Polack, Fernando P
collection PubMed
description We are ignoring evidence suggesting that the diagnosis of bronchiolitis encompasses several diseases with distinct underlying mechanisms, considerable heterogeneity in treatment responses, and ultimately different therapeutic targets. Understanding this heterogeneity may be the only way to deliver appropriate, stratified treatments.
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spelling pubmed-65818992019-06-21 The Syndrome We Agreed to Call Bronchiolitis Polack, Fernando P Stein, Renato T Custovic, Adnan J Infect Dis Perspectives We are ignoring evidence suggesting that the diagnosis of bronchiolitis encompasses several diseases with distinct underlying mechanisms, considerable heterogeneity in treatment responses, and ultimately different therapeutic targets. Understanding this heterogeneity may be the only way to deliver appropriate, stratified treatments. Oxford University Press 2019-07-15 2019-02-19 /pmc/articles/PMC6581899/ /pubmed/30783666 http://dx.doi.org/10.1093/infdis/jiz082 Text en © The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Perspectives
Polack, Fernando P
Stein, Renato T
Custovic, Adnan
The Syndrome We Agreed to Call Bronchiolitis
title The Syndrome We Agreed to Call Bronchiolitis
title_full The Syndrome We Agreed to Call Bronchiolitis
title_fullStr The Syndrome We Agreed to Call Bronchiolitis
title_full_unstemmed The Syndrome We Agreed to Call Bronchiolitis
title_short The Syndrome We Agreed to Call Bronchiolitis
title_sort syndrome we agreed to call bronchiolitis
topic Perspectives
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581899/
https://www.ncbi.nlm.nih.gov/pubmed/30783666
http://dx.doi.org/10.1093/infdis/jiz082
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