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Plastic bronchitis: A case report

Plastic bronchitis is a rare and underdiagnosed disease characterized by the formation and expectoration of bronchial casts of amorphous material, which can be potentially fatal. It is more frequent in pediatric population. Symptoms can range from chronic cough and dyspnea to respiratory failure dep...

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Autores principales: Grizales, Clara L., González, Lina M., Castrillon, Maria A., Sua, Luz F., Lores, Juliana, Aguirre, Marisol, Fernández-Trujillo, Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582060/
https://www.ncbi.nlm.nih.gov/pubmed/31245273
http://dx.doi.org/10.1016/j.rmcr.2019.100876
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author Grizales, Clara L.
González, Lina M.
Castrillon, Maria A.
Sua, Luz F.
Lores, Juliana
Aguirre, Marisol
Fernández-Trujillo, Liliana
author_facet Grizales, Clara L.
González, Lina M.
Castrillon, Maria A.
Sua, Luz F.
Lores, Juliana
Aguirre, Marisol
Fernández-Trujillo, Liliana
author_sort Grizales, Clara L.
collection PubMed
description Plastic bronchitis is a rare and underdiagnosed disease characterized by the formation and expectoration of bronchial casts of amorphous material, which can be potentially fatal. It is more frequent in pediatric population. Symptoms can range from chronic cough and dyspnea to respiratory failure depending on the area of the compromised airway. Casts are classified as type I when constituted by inflammatory cells and accompany diseases such as asthma and pneumonias; and type II when acellular and are associated with congenital heart diseases following procedures such as Fontan. We report the case of a male schoolchild with a history of complex congenital heart disease, treated with palliative surgery, evaluated in the emergency department for cough and respiratory distress. The mother referred expulsion of gelatinous material after coughing. During clinical evaluation, expulsion of bronchial casts was evidenced, suggesting a plastic bronchitis. He underwent a diagnostic and therapeutic bronchoscopy and received initial treatment with respiratory therapy, nebulized hypertonic saline solution, mucolytics, dornase alpha and nebulized heparin. The hospitalization revealed a stenosis of the right pulmonary artery, which was corrected with stent. The patient progressed satisfactorily with improvement of cough and expectoration. He was discharged with combined treatment, nebulized medications and those concerning his underlying disease.
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spelling pubmed-65820602019-06-26 Plastic bronchitis: A case report Grizales, Clara L. González, Lina M. Castrillon, Maria A. Sua, Luz F. Lores, Juliana Aguirre, Marisol Fernández-Trujillo, Liliana Respir Med Case Rep Case Report Plastic bronchitis is a rare and underdiagnosed disease characterized by the formation and expectoration of bronchial casts of amorphous material, which can be potentially fatal. It is more frequent in pediatric population. Symptoms can range from chronic cough and dyspnea to respiratory failure depending on the area of the compromised airway. Casts are classified as type I when constituted by inflammatory cells and accompany diseases such as asthma and pneumonias; and type II when acellular and are associated with congenital heart diseases following procedures such as Fontan. We report the case of a male schoolchild with a history of complex congenital heart disease, treated with palliative surgery, evaluated in the emergency department for cough and respiratory distress. The mother referred expulsion of gelatinous material after coughing. During clinical evaluation, expulsion of bronchial casts was evidenced, suggesting a plastic bronchitis. He underwent a diagnostic and therapeutic bronchoscopy and received initial treatment with respiratory therapy, nebulized hypertonic saline solution, mucolytics, dornase alpha and nebulized heparin. The hospitalization revealed a stenosis of the right pulmonary artery, which was corrected with stent. The patient progressed satisfactorily with improvement of cough and expectoration. He was discharged with combined treatment, nebulized medications and those concerning his underlying disease. Elsevier 2019-06-08 /pmc/articles/PMC6582060/ /pubmed/31245273 http://dx.doi.org/10.1016/j.rmcr.2019.100876 Text en © 2019 The Authors. Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Grizales, Clara L.
González, Lina M.
Castrillon, Maria A.
Sua, Luz F.
Lores, Juliana
Aguirre, Marisol
Fernández-Trujillo, Liliana
Plastic bronchitis: A case report
title Plastic bronchitis: A case report
title_full Plastic bronchitis: A case report
title_fullStr Plastic bronchitis: A case report
title_full_unstemmed Plastic bronchitis: A case report
title_short Plastic bronchitis: A case report
title_sort plastic bronchitis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582060/
https://www.ncbi.nlm.nih.gov/pubmed/31245273
http://dx.doi.org/10.1016/j.rmcr.2019.100876
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