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A cross-species whole genome siRNA screen in suspension-cultured Chinese hamster ovary cells identifies novel engineering targets

High-throughput siRNA screens were only recently applied to cell factories to identify novel engineering targets which are able to boost cells towards desired phenotypes. While siRNA libraries exist for model organisms such as mice, no CHO-specific library is publicly available, hindering the applic...

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Detalles Bibliográficos
Autores principales:	Klanert, Gerald, Fernandez, Daniel J., Weinguny, Marcus, Eisenhut, Peter, Bühler, Eugen, Melcher, Michael, Titus, Steven A., Diendorfer, Andreas B., Gludovacz, Elisabeth, Jadhav, Vaibhav, Xiao, Su, Stern, Beate, Lal, Madhu, Shiloach, Joseph, Borth, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582146/ https://www.ncbi.nlm.nih.gov/pubmed/31213643 http://dx.doi.org/10.1038/s41598-019-45159-2

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