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DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute

Prokaryotic Argonaute proteins (pAgos) constitute a diverse group of endonucleases of which some mediate host defense by utilizing small interfering DNA guides (siDNA) to cleave complementary invading DNA. This activity can be repurposed for programmable DNA cleavage. However, currently characterize...

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Detalles Bibliográficos
Autores principales:	Hegge, Jorrit W, Swarts, Daan C, Chandradoss, Stanley D, Cui, Tao Ju, Kneppers, Jeroen, Jinek, Martin, Joo, Chirlmin, van der Oost, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582352/ https://www.ncbi.nlm.nih.gov/pubmed/31069393 http://dx.doi.org/10.1093/nar/gkz306

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