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Programmable DNA cleavage by Ago nucleases from mesophilic bacteria Clostridium butyricum and Limnothrix rosea

Argonaute (Ago) proteins are key players in RNA interference in eukaryotes, where they function as RNA-guided RNA endonucleases. Prokaryotic Argonautes (pAgos) are much more diverse than their eukaryotic counterparts but their cellular functions and mechanisms of action remain largely unknown. Some...

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Detalles Bibliográficos
Autores principales:	Kuzmenko, Anton, Yudin, Denis, Ryazansky, Sergei, Kulbachinskiy, Andrey, Aravin, Alexei A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582412/ https://www.ncbi.nlm.nih.gov/pubmed/31114878 http://dx.doi.org/10.1093/nar/gkz379

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