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Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer
BACKGROUND: The human epidermal growth factor receptor (HER) family of transmembrane tyrosine kinases is overexpressed and correlates with poor prognosis and decreased survival in many cancers. The receptor family has been therapeutically targeted, yet tyrosine kinase inhibitors (TKIs) do not inhibi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582486/ https://www.ncbi.nlm.nih.gov/pubmed/31215437 http://dx.doi.org/10.1186/s12967-019-1939-7 |