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Hypoglycemic effects of esculeoside A are mediated via activation of AMPK and upregulation of IRS-1

BACKGROUND: Tomato fruit (Lycopersicon esculentum Mill.) has been suggested to be useful for the prevention of diabetes. Esculeoside A is the main saponin compounds in tomatoes. This study investigated the hypoglycemic effects and the underlying mechanism of esculeoside A in C57BLKS/Leprdb (db/db) m...

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Detalles Bibliográficos
Autores principales:	Yang, Ziming, Zhang, Li, Liu, Jinglei, Lu, Fenglai, Wang, Lei, Chen, Yueyuan, Li, Dianpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582491/ https://www.ncbi.nlm.nih.gov/pubmed/31215434 http://dx.doi.org/10.1186/s12906-019-2543-3

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