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Combination chemotherapy of valproic acid (VPA) and gemcitabine regulates STAT3/Bmi1 pathway to differentially potentiate the motility of pancreatic cancer cells

BACKGROUND: Gemcitabine is the standard first-line chemotherapy regimen for pancreatic cancer. However, its therapeutic value is substantially limited in pancreatic cancer patients due to occurrence of resistance towards gemcitabine. A strategy of combined chemo-regimens is widely employed in clinic...

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Detalles Bibliográficos
Autores principales:	Li, Hehe, Zhang, Zhengle, Gao, Chenggang, Wu, Shihong, Duan, Qingke, Wu, Heshui, Wang, Chunyou, Shen, Qiang, Yin, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582499/ https://www.ncbi.nlm.nih.gov/pubmed/31244991 http://dx.doi.org/10.1186/s13578-019-0312-0

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