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Relation of AURKB over-expression to low survival rate in BCRA and reversine-modulated aurora B kinase in breast cancer cell lines
BACKGROUND: New therapeutic drug for breast cancer (BRCA), especially triple negative BRCA (TNBC), is urgently needed. Even though 2-(4-morpholinoanilino)-6-cyclohexylaminopurine (reversine) is an aurora kinase inhibitor, it also inhibits some cancer cells and human BRCA cells. However, the potentia...
Autores principales: | Huang, Di, Huang, Yu, Huang, Zisheng, Weng, Jiefeng, Zhang, Shuai, Gu, Weili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582545/ https://www.ncbi.nlm.nih.gov/pubmed/31244554 http://dx.doi.org/10.1186/s12935-019-0885-z |
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