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Profile and outcomes of patients with acute complications of malaria presenting to an urban emergency department of a tertiary hospital in Tanzania

OBJECTIVES: In Tanzania, malaria ranks number three among the top ten causes of deaths in all age groups, however little is known about the utilisation of emergency department by patients with complications of malaria. We describe clinical presentation, resource utilization, and outcomes of acutely...

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Autores principales: Yusuph, Raya, Sawe, Hendry R., Nkondora, Paulina N., Mfinanga, Juma A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582575/
https://www.ncbi.nlm.nih.gov/pubmed/31215449
http://dx.doi.org/10.1186/s13104-019-4388-8
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author Yusuph, Raya
Sawe, Hendry R.
Nkondora, Paulina N.
Mfinanga, Juma A.
author_facet Yusuph, Raya
Sawe, Hendry R.
Nkondora, Paulina N.
Mfinanga, Juma A.
author_sort Yusuph, Raya
collection PubMed
description OBJECTIVES: In Tanzania, malaria ranks number three among the top ten causes of deaths in all age groups, however little is known about the utilisation of emergency department by patients with complications of malaria. We describe clinical presentation, resource utilization, and outcomes of acutely ill patients with complications of malaria presenting to an urban emergency department (ED) in Tanzania. RESULTS: We screened 405 patients which physicians had a clinical suspicion or diagnosis of malaria at ED. We enrolled 184 (45.5%) patients meeting WHO clinical and laboratory definition of malaria. The median age was 22 years (interquartile range 22–33 years), 105 (57%) were male, and overall 124 (67.4%) were self-referral. The use of insecticide treated nets (ITNs) in this group was 125 (67.4%). Fever 125 (67.9%), headache 56 (30.4%) and general body malaise 41 (22.2%) were the top three frequent complains, while tachycardia 83 (42.9%) was the most frequent abnormal vital sign. Overall, 21 (11.4%) patients had severe anaemia and 21 (11.4%) had abnormal renal function test. In ED 121/184 (65.8%) patients received antimalarial, 74/184 (40.2%) received antibiotics, 6/184 (3.3%) received antipyretic/analgesic and 5/20 (25%) patients with severe anaemia received blood transfusion. Overall, 99/184 (53.8%) patients were hospitalized, 3 (1.6%) died at the ED, and the overall hospital morality was 3.8%. Overall we found a substantial burden of patients with complications of malaria presenting in the largest public ED in Tanzania. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-019-4388-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-65825752019-06-26 Profile and outcomes of patients with acute complications of malaria presenting to an urban emergency department of a tertiary hospital in Tanzania Yusuph, Raya Sawe, Hendry R. Nkondora, Paulina N. Mfinanga, Juma A. BMC Res Notes Research Note OBJECTIVES: In Tanzania, malaria ranks number three among the top ten causes of deaths in all age groups, however little is known about the utilisation of emergency department by patients with complications of malaria. We describe clinical presentation, resource utilization, and outcomes of acutely ill patients with complications of malaria presenting to an urban emergency department (ED) in Tanzania. RESULTS: We screened 405 patients which physicians had a clinical suspicion or diagnosis of malaria at ED. We enrolled 184 (45.5%) patients meeting WHO clinical and laboratory definition of malaria. The median age was 22 years (interquartile range 22–33 years), 105 (57%) were male, and overall 124 (67.4%) were self-referral. The use of insecticide treated nets (ITNs) in this group was 125 (67.4%). Fever 125 (67.9%), headache 56 (30.4%) and general body malaise 41 (22.2%) were the top three frequent complains, while tachycardia 83 (42.9%) was the most frequent abnormal vital sign. Overall, 21 (11.4%) patients had severe anaemia and 21 (11.4%) had abnormal renal function test. In ED 121/184 (65.8%) patients received antimalarial, 74/184 (40.2%) received antibiotics, 6/184 (3.3%) received antipyretic/analgesic and 5/20 (25%) patients with severe anaemia received blood transfusion. Overall, 99/184 (53.8%) patients were hospitalized, 3 (1.6%) died at the ED, and the overall hospital morality was 3.8%. Overall we found a substantial burden of patients with complications of malaria presenting in the largest public ED in Tanzania. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-019-4388-8) contains supplementary material, which is available to authorized users. BioMed Central 2019-06-18 /pmc/articles/PMC6582575/ /pubmed/31215449 http://dx.doi.org/10.1186/s13104-019-4388-8 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Yusuph, Raya
Sawe, Hendry R.
Nkondora, Paulina N.
Mfinanga, Juma A.
Profile and outcomes of patients with acute complications of malaria presenting to an urban emergency department of a tertiary hospital in Tanzania
title Profile and outcomes of patients with acute complications of malaria presenting to an urban emergency department of a tertiary hospital in Tanzania
title_full Profile and outcomes of patients with acute complications of malaria presenting to an urban emergency department of a tertiary hospital in Tanzania
title_fullStr Profile and outcomes of patients with acute complications of malaria presenting to an urban emergency department of a tertiary hospital in Tanzania
title_full_unstemmed Profile and outcomes of patients with acute complications of malaria presenting to an urban emergency department of a tertiary hospital in Tanzania
title_short Profile and outcomes of patients with acute complications of malaria presenting to an urban emergency department of a tertiary hospital in Tanzania
title_sort profile and outcomes of patients with acute complications of malaria presenting to an urban emergency department of a tertiary hospital in tanzania
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582575/
https://www.ncbi.nlm.nih.gov/pubmed/31215449
http://dx.doi.org/10.1186/s13104-019-4388-8
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