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Development of a novel ssDNA aptamer targeting neutrophil gelatinase-associated lipocalin and its application in clinical trials

BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) is a promising biomarker of early diagnosis and prediction for acute kidney injury (AKI). However, the current program for NGAL detection is not extensively applied in clinics due to the high expense of antibodies. Nucleic acid aptamers a...

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Detalles Bibliográficos
Autores principales: Hong, Xiaoqian, Yan, Huihui, Xie, Fuan, Wang, Kaiyu, Wang, Qiang, Huang, Huijuan, Yang, Kunrong, Huang, Suhong, Zhao, Tingting, Wang, Junkai, Chen, Yunyun, Liu, Kuancan, Lan, Xiaopeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582607/
https://www.ncbi.nlm.nih.gov/pubmed/31215436
http://dx.doi.org/10.1186/s12967-019-1955-7

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