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National estimates of poisoning events related to liquid nicotine in young children treated in US hospital emergency departments, 2013–2017

BACKGROUND: An estimated 2 million youth (in 2017) and 7.9 million adults (in 2015) reported currently using electronic nicotine delivery systems (ENDS). Reports of poisoning events related to liquid nicotine (e-liquids) in ENDS have been on the rise, but current, nationally-representative estimates...

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Autores principales: Chang, Joanne T., Wang, Baoguang, Chang, Cindy M., Ambrose, Bridget K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582692/
https://www.ncbi.nlm.nih.gov/pubmed/31245259
http://dx.doi.org/10.1186/s40621-019-0188-9
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author Chang, Joanne T.
Wang, Baoguang
Chang, Cindy M.
Ambrose, Bridget K.
author_facet Chang, Joanne T.
Wang, Baoguang
Chang, Cindy M.
Ambrose, Bridget K.
author_sort Chang, Joanne T.
collection PubMed
description BACKGROUND: An estimated 2 million youth (in 2017) and 7.9 million adults (in 2015) reported currently using electronic nicotine delivery systems (ENDS). Reports of poisoning events related to liquid nicotine (e-liquids) in ENDS have been on the rise, but current, nationally-representative estimates of hospital-treated poisoning cases related to e-liquid nicotine exposure in the United States (US) are lacking. FINDINGS: We used National Electronic Injury Surveillance System (NEISS) data from 2013 to 2017 to calculate national estimates with 95% confidence intervals (CIs) of poisoning incidents related to e-liquid nicotine exposure. From 2013 to 2017, an estimated 4745 poisoning cases related to e-liquids among children under age five were treated in US hospital emergency departments; the number of cases increased from 181 (95% CI: 0–369) in 2013 to 1736 (95% CI, 871–2602) in 2015 and then decreased to 411 (95% CI, 84–738) in 2017. Most of the cases were treated and released; 4.1% were admitted to the hospital. The most common route of exposure was through ingestion (96.9%), and 2.6% of the cases were through dermal exposure. The highest amounts of e-liquids or nicotine ingested were 118.2mL, 1 bottle, and 100 mg, and the most common symptoms (63.6%) related to nicotine poisoning were nausea and vomiting. CONCLUSIONS: This study provides national estimates of poisoning cases associated with nicotine exposure from e-liquids among children under age five. Findings on e-liquid volume or nicotine dose, when available, provide important insights into exposures associated with toxicity in children. Since NEISS data do not include product codes specific to ENDS or provide information on poisoning severity, we used general keywords to capture these events, which might underestimate the population burden. Information from this study may complement efforts, such as public education, to prevent unintended exposure to nicotine in e-liquids among children. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s40621-019-0188-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-65826922019-06-26 National estimates of poisoning events related to liquid nicotine in young children treated in US hospital emergency departments, 2013–2017 Chang, Joanne T. Wang, Baoguang Chang, Cindy M. Ambrose, Bridget K. Inj Epidemiol Short Report BACKGROUND: An estimated 2 million youth (in 2017) and 7.9 million adults (in 2015) reported currently using electronic nicotine delivery systems (ENDS). Reports of poisoning events related to liquid nicotine (e-liquids) in ENDS have been on the rise, but current, nationally-representative estimates of hospital-treated poisoning cases related to e-liquid nicotine exposure in the United States (US) are lacking. FINDINGS: We used National Electronic Injury Surveillance System (NEISS) data from 2013 to 2017 to calculate national estimates with 95% confidence intervals (CIs) of poisoning incidents related to e-liquid nicotine exposure. From 2013 to 2017, an estimated 4745 poisoning cases related to e-liquids among children under age five were treated in US hospital emergency departments; the number of cases increased from 181 (95% CI: 0–369) in 2013 to 1736 (95% CI, 871–2602) in 2015 and then decreased to 411 (95% CI, 84–738) in 2017. Most of the cases were treated and released; 4.1% were admitted to the hospital. The most common route of exposure was through ingestion (96.9%), and 2.6% of the cases were through dermal exposure. The highest amounts of e-liquids or nicotine ingested were 118.2mL, 1 bottle, and 100 mg, and the most common symptoms (63.6%) related to nicotine poisoning were nausea and vomiting. CONCLUSIONS: This study provides national estimates of poisoning cases associated with nicotine exposure from e-liquids among children under age five. Findings on e-liquid volume or nicotine dose, when available, provide important insights into exposures associated with toxicity in children. Since NEISS data do not include product codes specific to ENDS or provide information on poisoning severity, we used general keywords to capture these events, which might underestimate the population burden. Information from this study may complement efforts, such as public education, to prevent unintended exposure to nicotine in e-liquids among children. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s40621-019-0188-9) contains supplementary material, which is available to authorized users. BioMed Central 2019-04-01 /pmc/articles/PMC6582692/ /pubmed/31245259 http://dx.doi.org/10.1186/s40621-019-0188-9 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Report
Chang, Joanne T.
Wang, Baoguang
Chang, Cindy M.
Ambrose, Bridget K.
National estimates of poisoning events related to liquid nicotine in young children treated in US hospital emergency departments, 2013–2017
title National estimates of poisoning events related to liquid nicotine in young children treated in US hospital emergency departments, 2013–2017
title_full National estimates of poisoning events related to liquid nicotine in young children treated in US hospital emergency departments, 2013–2017
title_fullStr National estimates of poisoning events related to liquid nicotine in young children treated in US hospital emergency departments, 2013–2017
title_full_unstemmed National estimates of poisoning events related to liquid nicotine in young children treated in US hospital emergency departments, 2013–2017
title_short National estimates of poisoning events related to liquid nicotine in young children treated in US hospital emergency departments, 2013–2017
title_sort national estimates of poisoning events related to liquid nicotine in young children treated in us hospital emergency departments, 2013–2017
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582692/
https://www.ncbi.nlm.nih.gov/pubmed/31245259
http://dx.doi.org/10.1186/s40621-019-0188-9
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